SEOM Clinical Guideline of management of soft-tissue sarcoma (2016)
Clin. transl. oncol. (Print)
; 18(12): 1213-1220, dic. 2016. graf
Article
in English
| IBECS
| ID: ibc-158637
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Soft-tissue sarcomas are uncommon and heterogeneous tumors of mesenchymal origin. A soft-tissue mass that is increasing in size, greater than 5 cm, or located under deep fascia are criteria for suspicion of sarcoma. Diagnosis, treatment, and management should preferably be performed by a multidisciplinary team in reference centers. MRI and lung CT scan are mandatory for local and distant assessment. A biopsy indicating histological type and grade is needed previous to the treatment. Wide surgical resection with tumor-free tissue margin is the primary treatment for localized disease. Radiotherapy is indicated in large, deep, high-grade tumors, or after marginal resection not likely of being improved with reexcision. Neoadjuvant and adjuvant chemotherapy improve survival in selected cases, usually in high-grade sarcomas of the extremities. In the case of metastatic disease, patients with exclusive lung metastasis could be considered for surgery. First-line treatment with anthracyclines (or in combination with ifosfamide) is the treatment of choice. New drugs have shown activity in second-line therapy and in specific histological subtypes (AU)
RESUMEN
No disponible
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Sarcoma
/
Decision Making
/
Dermoid Cyst
/
Image-Guided Biopsy
Type of study:
Practice guideline
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2016
Document type:
Article
Institution/Affiliation country:
Hospital Duran I Reynals/Spain
/
Hospital Universitario Gregorio Marañon/Spain
/
Hospital Universitario Miguel Servet/Spain
/
Hospital Universitario Virgen de la Victoria/Spain
/
Hospital Universitario de Canarias/Spain
/
Hospital Universitario de Vigo/Spain
/
Hospital Vall dHebro/Spain
/
Hospital Virgen del Rocio/Spain
/
Hospital de la Santa Creu i Sant Pau/Spain