Assessment of IgE-mediated food allergies in children with atopic dermatitis
Allergol. immunopatol
; 45(1): 77-81, ene.-feb. 2017. graf
Article
in English
| IBECS
| ID: ibc-158978
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND:
Atopic dermatitis (AD) is an inflammatory disease of the skin, which is characterised by a chronic relapsing course.AIM:
The aim of the study was to assign the prevalence of clinically active food allergies among a group of children between 3 months and 7 years of age, with AD.METHODS:
Eighty-eight children with AD were screened for specific IgE antibodies to food proteins. All patients with AD and specific IgE antibodies to food proteins were subjected to Oral Food Challenges (OFCs) with the relevant foods.RESULTS:
Food-sensitised patients with moderate levels of sIgE had clinically active food allergy to milk (39.28%) and egg (42.34%) on the basis of positive OFCs. High IgE and eosinophilia had a prevalence of almost 80% and 25%, regardless of concomitant food sensitisation and disease severity.CONCLUSIONS:
In this study, clinically active food allergies were recognised in 26.13% of children with AD. Nevertheless, no association was confirmed between food sensitisation and AD severity. High IgE and peripheral eosinophilia have not been found more prevalent among children with severe AD nor among children with food sensitisation. Infants and younger children with AD should be screened for an underlying food allergy, regardless of disease severityRESUMEN
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Collection:
National databases
/
Spain
Health context:
Neglected Diseases
Health problem:
Zoonoses
Database:
IBECS
Main subject:
Dermatitis, Atopic
/
Food Hypersensitivity
/
Hypersensitivity, Immediate
Type of study:
Etiology study
/
Risk factors
Limits:
Child
/
Child, preschool
/
Humans
Language:
English
Journal:
Allergol. immunopatol
Year:
2017
Document type:
Article
Institution/Affiliation country:
Aristotle University of Thessaloniki/Greece
/
Democritus University of Thrace/Greece