Is there a relationship between penile vasculogenic erectile dysfunction, platelet functions and eosinophil count? / Existe una relación entre la disfunción eréctil vasculogénica del pene, las funciones de plaquetas y el conteo de eosinófilos?
Rev. int. androl. (Internet)
; 15(2): 64-69, abr.-jun. 2017. tab
Article
in English
| IBECS
| ID: ibc-162807
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Purpose. Blood count parameters of patients referring with penile vasculogenic erectile dysfunction (ED) were examined in this study. It was investigated whether eosinophil count (EC), platelet count (PC) and mean platelet volume (MPV), values among the suspected predictive parameters which may affect vascular functions, have a contribution on ED pathology or not. Materials and methods. Patients referring erectile dysfunction complaint were evaluated. Depending on the medical story, ED degree was determined by measuring International Index of Erectile Function (IIEF). Values such as hormones, complete blood count and other laboratory markers were examined. Penile doppler ultrasonography (PDU) was performed in patients suspected to have vasculogenic ED. According to PDU result, patients with vascular deficiency were included in the penile vasculogenic ED group and patients with normal results were included in the control group. 49 patients participated in the study from the penile vasculogenic ED group and 30 patients from the control group. Intergroup comparisons were performed using the Mann-Whitney U test and the chi-square (χ2) test was used to assess the relationship between categorical variables within the patient groups. Results. Low IIEF score in vasculogenic ED group compared to the control group and high EC, MPV and PC values were detected to be statistically significant (p<0.001, p=0.026, p=0.009, p=0.029, respectively). No statistically significant difference was observed among the two groups when age, white blood cells, red blood cells or hemoglobin values are considered (p=0.332, p=0.235, p=0.127, p=0.696, respectively). Conclusion. High MPV value and platelet count showing the platelet functions and high eosinophil count are important factors which may play a role in penile vasculogenic ED etiopathogenesis (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Impotence, Vasculogenic
/
Mean Platelet Volume
/
Erectile Dysfunction
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
/
Male
Language:
English
Journal:
Rev. int. androl. (Internet)
Year:
2017
Document type:
Article
Institution/Affiliation country:
Department of Urology/Turkey
/
Kathane State Hospital/Turkey
/
Medical Park Hospital/Turkey
/
Necmettin Erbakan University/Turkey
/
Selcuk University/Turkey