Radiodensitometric study for evaluation of bone mineral density around dental implants after zoledronic acid treatment in ovariectomized rats
Med. oral patol. oral cir. bucal (Internet)
; 22(3): e377-e382, mayo 2017. ilus, tab, graf
Article
in English
| IBECS
| ID: ibc-163207
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND:
The purpose of this study was to evaluate the effects of intravenous zoledronic acid applied systemically on osseointegration of dental implants and the surrounding bone mineral density (BMD) in the ovariectomized rats. MATERIAL ANDMETHODS:
36 rats were divided into three groups control (CTRL), ovariectomy (OVX), and ovariectomy-zoledronic acid (OVX/ZOL). The rats in the CTRL group underwent sham surgery, while rats in OVX and OVX / ZOL group underwent ovariectomy. After 12 weeks, rats from OVX / ZOL were injected with 0.04 mg/ kg ZOL intravenously once a week for 6 weeks. The rats from CTRL and OVX groups were injected with 0.9% NaCl. Implants were placed in the left tibia. After 8 weeks, rats were sacrificed and tibia bones were removed for radiodensitometric examination. Digital radiographs of bones' lateral surface were taken. The BMD was measured by using radiographic analysis software.RESULTS:
Statistically significant differences were found between all groups (p < 0.05). While highest mean BMD values were observed in the CTRL group, the lowest were in the OVX group.CONCLUSIONS:
The systemic use of ZOL has increased the bone density around the implants inserted osteoporotic rat tibia
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Bone Density
/
Dental Implants
/
Densitometry
Limits:
Animals
Language:
English
Journal:
Med. oral patol. oral cir. bucal (Internet)
Year:
2017
Document type:
Article
Institution/Affiliation country:
Corlu State Hospital/Turkey
/
Health Science University/Turkey
/
Yeni Yuzyil University/Turkey