Effects of staff education and standardizing dosing and collection times on vancomycin trough appropriateness in ward patients
Pharm. pract. (Granada, Internet)
; 15(2): 0-0, abr.-jun. 2017. tab
Article
in English
| IBECS
| ID: ibc-164245
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background:
Many institutions have guidelines for initiation and monitoring, but not timing, of vancomycin.Objective:
Our objective was to evaluate vancomycin trough collection appropriateness before and after an initiative to change the dosing and trough collection times in ward patients.Methods:
A retrospective cohort study of ward patients from May 2014-16 who received scheduled intravenous vancomycin was performed. Nurse managers and pharmacists provided staff education. Differences between pre- and post-intervention groups were compared using student's t-test for continuous data and chi-square test for categorical data.Results:
Baseline characteristics were similar between the pre-intervention (n=124) and post-intervention (n=122) groups except for weight-based maintenance dose (15.3 mg/kg vs. 16.5 mg/kg, p=0.03) and percentage of troughs collected with morning labs (14% vs. 87%, p<0.001). Patients in the pre- and post-intervention groups received a similar frequency of loading doses (14.5% vs. 16%, p=0.68). There was no significant difference in percentage of vancomycin troughs collected appropriately at 30 (40% vs. 42%, p=0.72), 60 (57% vs. 63%, p=0.35), or 75 (60% vs. 68%, p=0.22) minutes from the scheduled time of the next dose.Conclusion:
Staff education and standardizing collection of vancomycin troughs with morning blood collections did not affect the percentage of appropriately collected vancomycin troughs (AU)RESUMEN
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Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Pharmacists
/
Vancomycin
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Drug Monitoring
/
Dose-Response Relationship, Drug
Type of study:
Etiology study
/
Incidence study
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Observational study
/
Risk factors
Limits:
Humans
Country/Region as subject:
North America
Language:
English
Journal:
Pharm. pract. (Granada, Internet)
Year:
2017
Document type:
Article
Institution/Affiliation country:
Central Arkansas Veterans Healthcare System/United States
/
University of Arkansas for Medical Sciences Medical Center/United States
/
University of Arkansas for Medical Sciences/United States