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Negative correlation between presence of reactive oxygen species and Sperm Motility Index in whole semen samples of infertile males / Correlación negativa entre la presencia de especies reactivas del oxígeno y el índice de movilidad espermática en muestras completas de semen de varones estériles
Kuroda, Shinnosuke; Yumura, Yasushi; Mori, Kohei; Yasuda, Kengo; Takeshima, Teppei; Kawahara, Takashi; Miyoshi, Yasuhide; Uemura, Hiroji; Iwasaki, Akira; Takashima, Kunitomo; Ikeda, Mario; Kondo, Yoshihito.
Affiliation
  • Kuroda, Shinnosuke; Yokohama Minato Red Cross Hospital. Department of Urology. Kanagawa. Japan
  • Yumura, Yasushi; Department of Urology. Reproductive Center. Department of Urology. Kanagawa. Japan
  • Mori, Kohei; Department of Urology. Reproductive Center. Department of Urology. Kanagawa. Japan
  • Yasuda, Kengo; Department of Urology. Reproductive Center. Department of Urology. Kanagawa. Japan
  • Takeshima, Teppei; Department of Urology. Reproductive Center. Department of Urology. Kanagawa. Japan
  • Kawahara, Takashi; Yokohama City University Medical Center. Department of Urology. Kanagawa. Japan
  • Miyoshi, Yasuhide; Yokohama City University Medical Center. Department of Urology. Kanagawa. Japan
  • Uemura, Hiroji; Yokohama City University Medical Center. Department of Urology. Kanagawa. Japan
  • Iwasaki, Akira; Department of Urology. Reproductive Center. Department of Urology. Kanagawa. Japan
  • Takashima, Kunitomo; Ebina Ladies' Clinic. Kanagawa. Japan
  • Ikeda, Mario; Ebina Ladies' Clinic. Kanagawa. Japan
  • Kondo, Yoshihito; Ebina Ladies' Clinic. Kanagawa. Japan
Rev. int. androl. (Internet) ; 15(3): 84-89, jul.-sept. 2017. tab, ilus
Article in English | IBECS | ID: ibc-164825
Responsible library: ES1.1
Localization: BNCS
ABSTRACT
Objective. To investigate the relationship between the Sperm Motility Index and the presence of reactive oxygen species in semen. Methods. We retrospectively analyzed Sperm Motility Index measured by the Sperm Quality Analyzer and reactive oxygen species levels in 92 semen samples of infertile male patients who visited the Ebina Ladies’ Clinic between September 2011 and June 2012. Using the same semen samples, we also analyzed 8 sperm parameters measured by computer-assisted semen analysis and validated the relationship with the Sperm Motility Index. Results. The presence of reactive oxygen species in semen was positive in 19 samples and negative in 73 samples. In the reactive oxygen species-positive group, there was a significant negative correlation between the logarithm of reactive oxygen species level and Sperm Motility Index (p = 0.039). Conclusions. This is the first study to find a significant negative correlation between Sperm Motility Index and reactive oxygen species level. This result indicates that the presence of reactive oxygen species in semen may inhibit the fertilization ability of spermatazoa as measured by the Sperm Motility Index (AU)
RESUMEN
Objetivo. Investigar la relación entre el índice de movilidad espermática y la presencia de especies reactivas del oxígeno en el semen. Métodos. Analizamos retrospectivamente el índice de movilidad espermática medido por el analizador de calidad del esperma y los niveles de especies reactivas del oxígeno en 92 muestras de semen de varones estériles que visitaron Ebina Ladies’ Clinic entre septiembre de 2011 y junio de 2012. Con las mismas muestras de semen también analizamos 8 parámetros del esperma medidos mediante un análisis de semen asistido por ordenador y validamos la relación con el índice de movilidad espermática. Resultados. La presencia de especies reactivas del oxígeno en el semen dio positivo en 19 muestras y negativo en 73. En el grupo positivo para especies reactivas del oxígeno hubo una correlación negativa significativa entre el logaritmo de nivel de especies reactivas del oxígeno y el índice de movilidad espermática (p = 0,039). Conclusiones. Este es el primer estudio que encuentra una correlación negativa significativa entre el índice de movilidad espermática y el nivel de especies reactivas del oxígeno. Este resultado indica que la presencia de especies reactivas del oxígeno en el semen podría inhibir la capacidad de fecundación de los espermatozoides según la medición del índice de movilidad espermática (AU)
Subject(s)
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Collection: National databases / Spain Database: IBECS Main subject: Semen / Sperm Motility / Reactive Oxygen Species / Infertility, Male Type of study: Observational study Limits: Humans / Male Language: English Journal: Rev. int. androl. (Internet) Year: 2017 Document type: Article Institution/Affiliation country: Department of Urology/Japan / Ebina Ladies' Clinic/Japan / Yokohama City University Medical Center/Japan / Yokohama Minato Red Cross Hospital/Japan
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Collection: National databases / Spain Database: IBECS Main subject: Semen / Sperm Motility / Reactive Oxygen Species / Infertility, Male Type of study: Observational study Limits: Humans / Male Language: English Journal: Rev. int. androl. (Internet) Year: 2017 Document type: Article Institution/Affiliation country: Department of Urology/Japan / Ebina Ladies' Clinic/Japan / Yokohama City University Medical Center/Japan / Yokohama Minato Red Cross Hospital/Japan
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