Enteral nutrition is associated with a decreased risk of surgical intervention in Crohn's disease patients with spontaneous intra-abdominal abscess
Rev. esp. enferm. dig
; 109(12): 834-842, dic. 2017. tab, graf
Article
in English
| IBECS
| ID: ibc-169191
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Background:
The impact of enteral nutrition (EN) on surgical risk in Crohns disease (CD) patients suffering from spontaneous intra-abdominal abscess (IAA) was evaluated.Methods:
CD patients diagnosed with spontaneous IAA from 2008 to 2015 were included in the study. The impact of EN on surgical risk was evaluated using both univariate and multivariate analyses.Results:
A total of 87 patients were enrolled, 66 (75.9%) were male. The mean age at the development of an abscess was 30.2 ± 10.1 years and the median duration of illness from CD diagnosis until the development of an abscess was three (2-6) years. After a median follow-up of 1.9 (1.1-2.9) years, surgical intervention was performed in 42 patients (48.3%). Patients treated with EN were less likely to require surgical intervention (26.1% vs 56.3%, p = 0.01). Multivariate analysis showed that EN was an independent protective factor for the risk of surgery with a hazard ratio of 0.27 (95% confidence interval 0.11-0.65, p = 0.004) after adjusting for abdominal pain, history of abdominal surgery, concomitant intestinal stenosis and prior use of antibiotics within three months.Conclusions:
Surgical intervention is common for CD patients with IAA. Appropriate application of EN may help obviate the need for surgical treatment (AU)RESUMEN
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Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Crohn Disease
/
Enteral Nutrition
/
Abdominal Abscess
Type of study:
Etiology study
/
Risk factors
Limits:
Humans
Language:
English
Journal:
Rev. esp. enferm. dig
Year:
2017
Document type:
Article
Institution/Affiliation country:
Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases/China
/
The Sixth Affiliated Hospital of Sun Yat-sen University/China