Tubérculo coroideo asintomático en un paciente con enfermedad de Crohn en tratamiento con adalimumab / Asymptomatic choroidal tubercle in a patient with Crohn's disease on adalimumab treatment
Arch. Soc. Esp. Oftalmol
; 93(3): 147-150, mar. 2018. ilus
Article
in Spanish
| IBECS
| ID: ibc-172249
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Introducción:
Adalimumab, un antifactor de necrosis tumoral que se utiliza en la enfermedad de Crohn activa (EC), se asocia con un mayor riesgo de tuberculosis. Caso clínico Se describe el caso de un varón de 48 años con EC activa en tratamiento con adalimumab. Después de 3 meses desarrolló una tuberculosis pulmonar miliar, y en un estudio oftalmológico se encontró un tubérculo coroideo no reactivo solitario temporal superior al disco óptico. La angiofluoresceingrafía mostró hiperfluorescencia tardía. Con la tomografía de coherencia óptica se observó una masa plana sin desprendimiento seroso de retina. El tubérculo coroideo regresó lentamente con la terapia antituberculosa.Discusión:
En pacientes con EC y en tratamiento con adalimumab, un tubérculo coroideo puede presentarse sin sintomatología vítreo-retiniana (AU)ABSTRACT
Introduction:
Adalimumab, an anti-tumour necrosis factor alpha therapy for active Crohn's disease (CD), is associated with increased risks of tuberculosis infection. Case report The case is presented of a 48 year-old male with active CD on treatment with adalimumab. After three months, he developed a miliary pulmonary tuberculosis infection, with a solitary non-reactive choroidal tubercle temporal-superior to the optic disc being found in an ophthalmological study. Fluorescein angiography showed late hyperfluorescence in a staining pattern. Optic coherence tomography showed a flat mass without serous retinal detachment. The choroidal tubercle slowly regressed with antituberculosis therapy.Discussion:
Choroidal tubercles with no vitreo-retinal symptomatology can be present in patients with CD and on treatment with adalimumab (AU)
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Collection:
National databases
/
Spain
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Tuberculosis
Database:
IBECS
Main subject:
Crohn Disease
/
Choroid Diseases
/
Tuberculosis, Ocular
/
Adalimumab
Type of study:
Etiology study
Limits:
Humans
/
Male
Language:
Spanish
Journal:
Arch. Soc. Esp. Oftalmol
Year:
2018
Document type:
Article
Institution/Affiliation country:
Hospital Clínico Universitario/España