¿Se podría diagnosticar la enfermedad celíaca solo con serología? / Can the diagnosis of celiac disease be based on serologic tests alone?
Pediatr. aten. prim
; 20(77): 79-82, ene.-mar. 2018.
Article
in Spanish
| IBECS
| ID: ibc-173587
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Conclusiones de los autores del estudio se validan, mediante un estudio prospectivo, dos procedimientos basados en la determinación de anticuerpos antitransglutaminasa y anticuerpos antigliadina-deaminada para la identificación de pacientes pediátricos con y sin enfermedad celíaca, sin necesidad de biopsia. Comentario de los revisores aunque las determinaciones serológicas son útiles para el diagnóstico de enfermedad celíaca y pueden permitir el diagnóstico sin necesidad de recurrir a la biopsia duodenal, parece razonable continuar con las recomendaciones actuales, especialmente en grupos de pacientes de bajo riesgo de enfermedad
ABSTRACT
Authors2 conclusions:
in a prospective study, we validated two procedures based on the determination of anti-glutaminase and anti-gliadin-deaminated antibodies for the identification of pediatric patients with or without celiac disease, without biopsy. Reviewers commentary although serological determinations are useful for the diagnosis of celiac disease and can allow diagnosis without duodenal biopsy, it seems reasonable to continue with the current recommendations, especially in groups of patients with low risk of disease
Full text:
Available
Collection:
National databases
/
Spain
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 7: Evidence and knowledge in health
Database:
IBECS
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Celiac Disease
/
Transglutaminases
/
Predictive Value of Tests
/
Evidence-Based Medicine
/
Gliadin
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Etiology study
/
Practice guideline
/
Incidence study
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Observational study
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Prognostic study
/
Risk factors
Limits:
Adolescent
/
Child
/
Child, preschool
/
Humans
/
Infant
Language:
Spanish
Journal:
Pediatr. aten. prim
Year:
2018
Document type:
Article
Institution/Affiliation country:
Hospital Infantil Universitario La Paz/España
/
Hospital Universitario Infanta Leonor/España