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¿Se podría diagnosticar la enfermedad celíaca solo con serología? / Can the diagnosis of celiac disease be based on serologic tests alone?
Molina Arias, Manuel; Pérez-Moneo Agapito, Begoña.
Affiliation
  • Molina Arias, Manuel; Hospital Infantil Universitario La Paz. Servicio de Gastroenterología y Nutrición. Madrid. España
  • Pérez-Moneo Agapito, Begoña; Hospital Universitario Infanta Leonor. Madrid. España
Pediatr. aten. prim ; 20(77): 79-82, ene.-mar. 2018.
Article in Spanish | IBECS | ID: ibc-173587
Responsible library: ES1.1
Localization: BNCS
RESUMEN
Conclusiones de los autores del estudio se validan, mediante un estudio prospectivo, dos procedimientos basados en la determinación de anticuerpos antitransglutaminasa y anticuerpos antigliadina-deaminada para la identificación de pacientes pediátricos con y sin enfermedad celíaca, sin necesidad de biopsia. Comentario de los revisores aunque las determinaciones serológicas son útiles para el diagnóstico de enfermedad celíaca y pueden permitir el diagnóstico sin necesidad de recurrir a la biopsia duodenal, parece razonable continuar con las recomendaciones actuales, especialmente en grupos de pacientes de bajo riesgo de enfermedad
ABSTRACT
Authors2

conclusions:

in a prospective study, we validated two procedures based on the determination of anti-glutaminase and anti-gliadin-deaminated antibodies for the identification of pediatric patients with or without celiac disease, without biopsy. Reviewers’ commentary although serological determinations are useful for the diagnosis of celiac disease and can allow diagnosis without duodenal biopsy, it seems reasonable to continue with the current recommendations, especially in groups of patients with low risk of disease
Subject(s)
Full text: Available Collection: National databases / Spain Health context: Sustainable Health Agenda for the Americas Health problem: Goal 7: Evidence and knowledge in health Database: IBECS Main subject: Enzyme-Linked Immunosorbent Assay / Celiac Disease / Transglutaminases / Predictive Value of Tests / Evidence-Based Medicine / Gliadin Type of study: Controlled clinical trial / Diagnostic study / Etiology study / Practice guideline / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Child / Child, preschool / Humans / Infant Language: Spanish Journal: Pediatr. aten. prim Year: 2018 Document type: Article Institution/Affiliation country: Hospital Infantil Universitario La Paz/España / Hospital Universitario Infanta Leonor/España
Full text: Available Collection: National databases / Spain Health context: Sustainable Health Agenda for the Americas Health problem: Goal 7: Evidence and knowledge in health Database: IBECS Main subject: Enzyme-Linked Immunosorbent Assay / Celiac Disease / Transglutaminases / Predictive Value of Tests / Evidence-Based Medicine / Gliadin Type of study: Controlled clinical trial / Diagnostic study / Etiology study / Practice guideline / Incidence study / Observational study / Prognostic study / Risk factors Limits: Adolescent / Child / Child, preschool / Humans / Infant Language: Spanish Journal: Pediatr. aten. prim Year: 2018 Document type: Article Institution/Affiliation country: Hospital Infantil Universitario La Paz/España / Hospital Universitario Infanta Leonor/España
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