Prevalencia de enfermedad pulmonar obstructiva crónica en 6 aglomerados urbanos de Argentina: el estudio EPOC. AR / Prevalence of COPD in 6 Urban Clusters in Argentina: The EPOC. AR Study
Arch. bronconeumol. (Ed. impr.)
; 54(5): 260-269, mayo 2018. map, tab, graf
Article
in Spanish
| IBECS
| ID: ibc-176140
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Introducción:
La prevalencia de la enfermedad pulmonar obstructiva crónica (EPOC) en Argentina no había sido estudiada.Objetivos:
Determinar la prevalencia de EPOC y rasgos clínicos relevantes en una muestra representativa. Material ymétodos:
Estudio de corte transversal en población ≥40 años en 6 aglomerados urbanos seleccionada aleatoriamente mediante muestreo por conglomerados. Se aplicó una encuesta estructurada y espirometrías pre y postbroncodilatador (PBD). Se definió EPOC en quienes presentaban un cociente FEV1/FVC PBD<0,7. Se estimó la prevalencia total y para cada aglomerado con intervalo de confianza del 95% (IC).Resultados:
Se realizaron 4.599 encuestas y 3.999 espirometrías, de las cuales 3.469 fueron útiles (86,8%). La prevalencia de EPOC fue de 14,5% (IC 13,4-15,7). La distribución de los casos compatibles con EPOC según FEV1 (GOLD-2017) fue 1 38% (IC 34-43); 2 52% (IC 47-56); 3 10% (IC 7-13); y 4 1% (IC 0,-2) y de acuerdo al modelo combinado ABCD (GOLD 2017) A 52% (IC 47-56); B 43% (IC 39-48); C 1% (IC 0-2) y D 4% (IC 2-6). El subdiagnóstico fue del 77,4% (IC 73,7-81,1%) y el error diagnóstico de 60,7% (IC 55,1-66,3%). Encontramos asociación significativa de presencia de EPOC con edad (OR 3,77 en 50-59 años a 19,23 en >80 años), sexo masculino (OR 1,62; IC 1,31-2), tabaquismo (OR 1,95; IC 1,49-2,54), nivel socieconómico bajo (OR 1,33; IC 1,02-1,73) y antecedentes de tuberculosis (OR 3,3; IC 1,43-7,62).Conclusiones:
Se estima que más de 2,3 millones de argentinos padecen EPOC con elevada tasa de subdiagnóstico y error diagnósticoABSTRACT
Introduction:
The prevalence of chronic obstructive pulmonary disease (COPD) has not been studied in Argentina.Objectives:
To determine the prevalence and relevant clinical characteristics of COPD in a representative sample. Material andmethods:
We performed a cross-sectional study in a population of adults aged ≥ 40 years randomly selected by cluster sampling in 6 urban locations. Subjects answered a structured survey and performed pre- and post-bronchodilator spirometry (PBD). COPD was defined as FEV1/FVC ratio < 0.7 predicted value. The total prevalence was estimated for each cluster with its 95% confidence interval (CI).Results:
Of 4,599 surveys and 3,999 spirometries, 3,469 were considered of adequate quality (86.8%) for our study. The prevalence of COPD was 14.5% (CI 13.4-15.7). The distribution of COPD cases according to FEV1 (GOLD 2017) was stage 1 38% (CI 34-43); stage 2 52% (CI 47-56); stage 3 10% (CI 7-13); and stage 4 1% (CI 0-2), and according to the refined ABCD (GOLD 2017) assessment A 52% (CI 47-56); B 43% (CI 39-48); C 1% (CI 0-2); D 4% (CI 2-6). The rate of underdiagnosis was 77.4% (CI 73.7-81.1%) and diagnostic error 60.7% (CI 55.1-66.3%). A significant association was found between COPD and age (OR 3.77 in individuals 50-59 years of age and 19.23 in those > 80 years), male gender (OR 1.62; CI 1.31-2), smoking (OR 1.95; CI 1.49-2.54), low socioeconomic status (OR 1.33; CI 1.02-1.73), and previous tuberculosis (OR 3.3; CI 1.43-7.62).Conclusions:
We estimate that more than 2.3 million Argentineans have COPD, with high rates of underdiagnosis and diagnostic error
Full text:
Available
Collection:
National databases
/
Spain
Health context:
SDG3 - Target 3A Strengthen the implementation of the WHO Framework Convention on Tobacco Control
/
SDG3 - Health and Well-Being
/
Neglected Diseases
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SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Education, Communication, Training and Public Awareness
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Target 3.4: Reduce premature mortality due to noncommunicable diseases
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Target 3.5: Prevention and treatment of consumption of psychoactive substances
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Tuberculosis
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Tuberculosis
Database:
IBECS
Main subject:
Tobacco Use Disorder
/
Risk Factors
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Pulmonary Disease, Chronic Obstructive
Type of study:
Controlled clinical trial
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Etiology study
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Observational study
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Prevalence study
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Prognostic study
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Qualitative research
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Risk factors
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Screening study
Limits:
Adult
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Aged
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Female
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Humans
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Male
Country/Region as subject:
South America
/
Argentina
Language:
Spanish
Journal:
Arch. bronconeumol. (Ed. impr.)
Year:
2018
Document type:
Article
Institution/Affiliation country:
Hospital Dr. Antonio A. Cetrángolo/Argentina
/
Hospital Interzonal Especializado de Agudos y Crónicos San Juan de Dios/Argentina
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Hospital María Ferrer/Argentina
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Ministerio de Salud de la Nación/Argentina
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Universidad Autónoma de Madrid/España
/
Universidad de Buenos Aires/Argentina