Different subpopulations of mild cognitive impairment are identified by using Petersen's or DSM-5 criteria
Eur. j. psychiatry
; 31(2): 80-86, abr.-jun. 2017. tab
Article
in English
| IBECS
| ID: ibc-179728
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
OBJECTIVES:
In view of differences in the prevalence and conversion rate to dementia of Petersen's (P-MCI) and DSM-5's (DSM-5-MCI) categories of mild cognitive impairment, this paper is intended to examine the diagnostic agreement between the categories and to analyze clinical factors related to the potential discrepancies.METHOD:
A representative population cohort of 4580 dementia-free individuals 55+ years of age was examined in Zaragoza, Spain (ZARADEMP). Validated Spanish versions of instruments, including the Geriatric Mental State-AGECAT, were used for assessment. Research psychiatrists diagnosed DSM-5-MCI and P-MCI following operationalized criteria. Between-category differences were analyzed, and the statistical methods included the calculation of Cohen's Kappa coefficients of agreement, and the McNemar's test to compare the performance of the intermediate cognitive definitions.RESULTS:
Diagnostic concordance in the classification of MCI cases was very limited. In the total sample, 2.7% of individuals did not meet the P-MCI criteria but met the DSM-5-MCI criteria; and 6.4% met the P-MCI criteria, but not the DSM-5-MCI criteria. Overlap of both categories was observed in only 0.6%. The overall Kappa (agreement between both MCI categories) was 0.08 (95% CI 0.04-0.12; p < 0.001). While no between-category significant differences was observed in cognitive scores, relevant differences in the populations identified had to do with demographic, non-cognitive psychopathological factors, activities of daily living and general health factors.CONCLUSIONS:
This study shows 'poor' diagnostic agreement between the P-MCI and the DSM-5-MCI categories. The non-cognitive factors should receive special attention when trying to improve the validity of the MCI constructRESUMEN
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Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Disease Progression
/
Diagnostic and Statistical Manual of Mental Disorders
/
Cognitive Dysfunction
Limits:
Humans
Language:
English
Journal:
Eur. j. psychiatry
Year:
2017
Document type:
Article
Institution/Affiliation country:
Universidad de Zaragoza/Spain