Linfoma de Hodgkin en enfermedad inflamatoria intestinal tratado con tiopurinas. Presentación de un caso y revisión de la literatura / Hodgkin's lymphoma associated with inflammatory bowel disease treated with thiopurines. A case report and review of the literature
Rev. esp. patol
; 52(4): 242-245, oct.-dic. 2019. ilus
Article
in Spanish
| IBECS
| ID: ibc-191944
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
El riesgo asociado de desarrollar una enfermedad linfoproliferativa en la enfermedad inflamatoria intestinal (EII) es un tema controvertido desde hace décadas y se discute si el riesgo se asocia a la inflamación crónica de la EII per se o a los tratamientos de la misma, especialmente los fármacos tiopurínicos (azatioprina y mercaptopurina) y los agentes anti-TNF-alfa. Presentamos un caso excepcional de un varón de 35 años diagnosticado de enfermedad de Crohn con 17 años y en tratamiento con azatioprina, que presentó años después, un linfoma de Hodgkin intestinal
ABSTRACT
The risk of developing a lymphoproliferative disease associated with inflammatory bowel disease (IBD) has been a controversial issue for decades; it is debatable whether the risk is associated with the chronic inflammation of IBD per se or its treatment, especially with thiopurine drugs (azathioprine and mercaptopurine) and anti-TNF-alfa agents. We present an unusual case of a 35-year-old man who had been diagnosed with Crohn's disease at age 17 and treated with azathioprine, presenting years later with an intestinal Hodgkin's lymphoma
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Azathioprine
/
Hodgkin Disease
/
Inflammatory Bowel Diseases
/
Crohn Disease
/
Intestinal Neoplasms
/
Mercaptopurine
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. esp. patol
Year:
2019
Document type:
Article
Institution/Affiliation country:
Hospital General de Jerez de la Frontera/España
/
Hospital de Jerez de la Frontera/España