Children with eosinophilic esophagitis in real life: 10 years' experience with a focus on allergic management
Allergol. immunopatol
; 48(3): 244-250, mayo-jun. 2020. graf, tab
Article
in English
| IBECS
| ID: ibc-192026
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
INTRODUCTION AND OBJECTIVES:
Eosinophilic esophagitis (EoE) is frequently miss-diagnosed or overlooked for several years because of the invasiveness of investigations and the non-specificity of symptoms in childhood. Due to the lack of specific recommendations in children, its management remains very heterogeneous, especially concerning allergy testing. The aim of this study is to analyze our population and practices, in comparison with the literature, with a focus on allergic management, to harmonize and optimize our practice. MATERIAL ANDMETHODS:
We included all children with a diagnosis of EoE at the Hospital Femme Mere Enfant, Bron, France. Data were collected via retrospective chart review.RESULTS:
108 patients were included with an average age of 9.5 years. Average delay before diagnosis was 6.65 years. Symptoms varied with age, with a predominance of vomiting (60% of patients), feeding difficulties (72%) and growth difficulties (24%) in children < 5 years, whereas older children often presented with feeding blockage (64%) and dysphagia (61%). Cough was frequent in our cohort (18.5%), especially in children < 10 years (38.5% between three and five years). The allergic background was frequent (70.3%) and 80% of our patients benefited from allergy testing. Allergy testing was particularly useful to guide therapy as elimination diet represented an effective treatment in 60% of our patientsCONCLUSIONS:
Allergy testing has to be harmonized to include major allergens (egg, milk, peanut, fish, wheat, and soy), including prick and patch tests. Allergy-testing based diet seemed to be the best compromise between efficiency and constraints, especially in mono-sensitized patientsRESUMEN
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Immunologic Techniques
/
Eosinophilic Esophagitis
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
English
Journal:
Allergol. immunopatol
Year:
2020
Document type:
Article
Institution/Affiliation country:
Hospices Civils de Lyon/France
/
Hôpital Femme-Mère-Enfant/France
/
Université Claude Bernard Lyon 1/France