Elevated D-Dimer and acute pulmonary embolism in COVID-19 patients / Dímero-D elevado y tromboembolismo pulmonar agudo en pacientes con COVID-19
J. negat. no posit. results
; 5(12): 1516-1527, dic. 2020. ilus, tab
Article
in English
| IBECS
| ID: ibc-195998
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
INTRODUCTION:
It has been determined that patients with SARS-CoV-2 infection and severe pneumonia with elevated D-dimer values can develop acute pulmonary thromboembolism (APE) as a complication, being one of the causes related to mortality in this group of patients.METHODS:
A retrospective analysis of 12 patients diagnosed with SARS-CoV-2 infection with high clinical suspicion of APE confirmed by computed tomography pulmonary angiopgraphy (CTPA) was performed and the described findings are described.RESULTS:
12 patients with diagnosis of severe pneumonia, elevated D-dimer 9.2 μg / ml (1.4 - ˃20 μg / mL) and confirmation of SARS-CoV-2 infection through real-time reverse transcription polymerasa chain reaction (RT-PCR). APEs were observed mainly in segmental arteries (75%) and main arteries (25%). Pneumonia with patched areas of bilateral ground glass opacities was observed in 100% of the sample as a typical finding of SARS-CoV-2 infection.CONCLUSION:
SARS-CoV-2 infection is related to elevation of D-dimer and APE. The CTPA determines the diagnosis, severity and timely management (anticoagulation) of patients with APE. Therefore CTPA should be considered in all patients with elevated D-dimer or clinical worsening
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Pneumonia, Viral
/
Pulmonary Embolism
/
Biomarkers
/
Coronavirus Infections
/
Pandemics
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
J. negat. no posit. results
Year:
2020
Document type:
Article
Institution/Affiliation country:
Hospital General de Segovia/Spain
/
Hospital Universitario La Paz/Spain