Risk factors related to oral candidiasis in patients with primary Sjögren's síndrome
Med. oral patol. oral cir. bucal (Internet)
; 25(5): e700-e705, sept. 2020. tab, graf
Article
in English
| IBECS
| ID: ibc-196527
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
BACKGROUND:
Candidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren's syndrome (pSS) and to study the possible factors associated with this infection. MATERIAL ANDMETHODS:
An observational cross-sectional study was conducted in 61 pSS patients (60 women, 1 man, mean age 57.64 ± 13.52) where patient based information (demographic and medical, tobacco and alcohol consumption history), intraoral parameters (presence of dentures, clinical signs of candidiasis), salivary analytical information (number of Candida albicans as colony-forming units per millilitre (CFU/mL), salivary pH levels, unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected.RESULTS:
13.1% of pSS patients presented oral signs of candidiasis. Denture stomatitis and angular cheilitis were the most common lesions. 87.5% of patients with clinical candidiasis presented reduced pH levels and salivary flow in both UWS and SWS. A significant statistical negative correlation was found between CFU/mL of Candida albicans and levels of UWS and SWS. A negative correlation was found between pH levels and CFU/mL, although not statistically significant.CONCLUSIONS:
A reduced salivary flow may predispose pSS patients to Candida albicans overgrowth, which may show with clinical signs. Preventive measures are of great importance to avoid and to treat this condition promptlyRESUMEN
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Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Candida albicans
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Candidiasis, Oral
/
Sjogren's Syndrome
Limits:
Adult
/
Aged
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Female
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Humans
/
Male
Language:
English
Journal:
Med. oral patol. oral cir. bucal (Internet)
Year:
2020
Document type:
Article
Institution/Affiliation country:
Complutense University/Spain
/
Hospital 12 de Octubre/Spain
/
Hospital La Paz/Spain
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Hospital Puerta de Hierro/Spain