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Can systemic immune inflammation index at admission predict in-hospital mortality in chronic kidney disease patients with SARS-CoV-2 infection? / ¿Puede el índice de inflamación inmunitaria sistémica al ingreso predecir la mortalidad hospitalaria al ingreso de pacientes con enfermedad renal crónica e infección por SARS-CoV-2?
Ozdemir, Arzu; Kocak, Sibel Yucel; Nur Karabela, Semsi; Yılmaz, Mürvet.
Affiliation
  • Ozdemir, Arzu; University of Health Sciences. Department of Nephrology. Bakirkoy Dr. Sadi Konuk Education and Research Hospital. Istanbul. Turkey
  • Kocak, Sibel Yucel; University of Health Sciences. Department of Nephrology. Bakirkoy Dr. Sadi Konuk Education and Research Hospital. Istanbul. Turkey
  • Nur Karabela, Semsi; University of Health Sciences. Department of Infectious Disease and Microbiology. Bakirkoy Dr. Sadi Konuk Education and Research Hospital. Istanbul. Turkey
  • Yılmaz, Mürvet; University of Health Sciences. Department of Nephrology. Bakirkoy Dr. Sadi Konuk Education and Research Hospital. Istanbul. Turkey
Nefrología (Madrid) ; 42(5): 549-558, sept.-oct. 2022. tab, graf
Article in En | IBECS | ID: ibc-211252
Responsible library: ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background and aim: Patients with chronic kidney disease (CKD) are susceptible to SARS-CoV-2 infection and more prone to develop severe disease. It is important to know predictors of poor outcomes to optimize the strategies of care.Methods: 93 patients with CKD and 93 age-sex matched patients without CKD were included in the study. Data on demographic, clinical features, hematological indices and outcomes were noted and compared between the groups. Neutrophile to lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation index (SII) (platelet counts×neutrophil counts/lymphocyte counts) and lymphocyte-to-CRP ratio (LCR) were calculated on admission and the association of these markers with disease mortality in CKD patients was identified. (AU)
RESUMEN
Antecedentes y objetivo: Los pacientes con enfermedad renal crónica (ERC) son susceptibles a la infección por SARS-CoV-2 y más propensos a desarrollar una enfermedad grave. Es importante conocer los predictores de los malos resultados para optimizar las estrategias de atención. Métodos: Se incluyeron en el estudio 93 pacientes con ERC y 93 pacientes sin ERC, emparejados por edad y sexo. Los datos sobre las características demográficas, clínicas, índices hematológicos y resultados, se anotaron y compararon entre los grupos. La proporción de neutrófilos a linfocitos (NLR), la proporción de plaquetas a linfocitos (PLR), el índice de inflamación inmunitaria sistémica (SII) (recuentos de plaquetas×recuentos de neutrófilos/recuentos de linfocitos) y la proporción de linfocitos a PCR (LCR) se calcularon en el momento de la admisión y se identificó la asociación de estos marcadores con la mortalidad por enfermedad en pacientes con ERC. (AU)
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Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Coronavirus Infections / Severe acute respiratory syndrome-related coronavirus / Renal Insufficiency, Chronic / Pandemics Limits: Adult / Aged / Female / Humans / Male Language: En Journal: Nefrología (Madrid) Year: 2022 Document type: Article

Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Coronavirus Infections / Severe acute respiratory syndrome-related coronavirus / Renal Insufficiency, Chronic / Pandemics Limits: Adult / Aged / Female / Humans / Male Language: En Journal: Nefrología (Madrid) Year: 2022 Document type: Article