Low prevalence of asthma in Mexican children and adults with a positive rtRT-PCR test for SARS-CoV-2: a cross-sectional study during the 2020 pandemic
Allergol. immunopatol
; 49(3): 1-7, mayo 2021. ilus, tab
Article
in English
| IBECS
| ID: ibc-214259
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background:
It has recently been argued that asthma does not increase the risk of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. If so, the prevalence of asthma in subjects diagnosed with COVID-19 should be lower than in the general population.Objective:
To determine the prevalence of asthma in Mexican children and adults with SARS-CoV-2 infection.Methods:
A public database of the Epidemiological Surveillance System for Viral Respiratory Disease in Mexico was analyzed. Those who underwent the real-time reverse transcriptase-polymerase chain reaction-SARS-CoV-2 (rtRT-PCR-SARS-CoV-2) test from February 27 to June 21, 2020, were included. In addition to the prevalence of asthma, some factors associated with it were investigated.Results:
Data from 417,366 subjects were analyzed. Asthma prevalence in children, adults, and global were 3.7%, 3.3%, and 3.3%, respectively. Although the asthma prevalence was lower in SARS-CoV-2 positive over negative patients, significant differences were only found in adults (2.8% vs. 3.7% respectively; odds ratio (OR) = 0.74; 95% confidence interval (CI) 0.710.77); but not in children (3.5% vs. 3.8%, respectively; OR = 0.91; 95%CI 0.761.10). Multivariate analysis showed in younger than 18 years that girls and immunosuppression were factors associated with a decrease in the odds to develop asthma. In adults, asthma was positively associated with females, obesity, smoking, immunosuppression, chronic obstructive pulmonary disease, arterial hypertension, and cardiovascular disease.Conclusion:
The prevalence of asthma in child and adult were lower than those previously reported. Our study seems to support the hypothesis that asthma patients have a lower risk of SARS-CoV-2 infection. Further studies are required to demonstrate the consistency of our findings (AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Asthma
/
Coronavirus Infections
/
Pandemics
Limits:
Adolescent
/
Adult
/
Aged
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Child
/
Child, preschool
/
Female
/
Humans
/
Male
Country/Region as subject:
Mexico
Language:
English
Journal:
Allergol. immunopatol
Year:
2021
Document type:
Article
Institution/Affiliation country:
Hospital Civil de Guadalajara Dr. Juan I. Menchaca/México
/
Nuevo Hospital Civil de Guadalajara Dr. Juan I. Menchaca/México
/
Nuevo Hospital Civil de Guadalajara Dr. Juan I. Menchaca/México
/
Universidad Veracruzana/México