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Low prevalence of asthma in Mexican children and adults with a positive rtRT-PCR test for SARS-CoV-2: a cross-sectional study during the 2020 pandemic
Bedolla-Barajas, Martím; Morales-Romero, Jaime; Bedolla-Pulido, Tonatiuh Ramses; Meza-López, Carlos; Robles-Figueroa, Martín; Pulido-Guillén, Norma Angélica; Orozco-Alatorre, Luis Gustavo; Andrade-Castellanos, Carlos Alberto.
Affiliation
  • Bedolla-Barajas, Martím; Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca. Servicio de Alergia e Inmunología Clínica. Guadalajara. México
  • Morales-Romero, Jaime; Universidad Veracruzana. Instituto de Salud Pública. Veracruz. México
  • Bedolla-Pulido, Tonatiuh Ramses; Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Servicio de Pediatría. Guadalajara. México
  • Meza-López, Carlos; Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Servicio de Pediatría. Guadalajara. México
  • Robles-Figueroa, Martín; Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Servicio de Medicina Interna. Guadalajara. México
  • Pulido-Guillén, Norma Angélica; s.af
  • Orozco-Alatorre, Luis Gustavo; Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Servicio de Pediatría. Guadalajara. México
  • Andrade-Castellanos, Carlos Alberto; Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Servicio de Medicina Interna. Guadalajara. México
Allergol. immunopatol ; 49(3): 1-7, mayo 2021. ilus, tab
Article in English | IBECS | ID: ibc-214259
Responsible library: ES1.1
Localization: ES15.1 - BNCS
ABSTRACT

Background:

It has recently been argued that asthma does not increase the risk of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. If so, the prevalence of asthma in subjects diagnosed with COVID-19 should be lower than in the general population.

Objective:

To determine the prevalence of asthma in Mexican children and adults with SARS-CoV-2 infection.

Methods:

A public database of the Epidemiological Surveillance System for Viral Respiratory Disease in Mexico was analyzed. Those who underwent the real-time reverse transcriptase-polymerase chain reaction-SARS-CoV-2 (rtRT-PCR-SARS-CoV-2) test from February 27 to June 21, 2020, were included. In addition to the prevalence of asthma, some factors associated with it were investigated.

Results:

Data from 417,366 subjects were analyzed. Asthma prevalence in children, adults, and global were 3.7%, 3.3%, and 3.3%, respectively. Although the asthma prevalence was lower in SARS-CoV-2 positive over negative patients, significant differences were only found in adults (2.8% vs. 3.7% respectively; odds ratio (OR) = 0.74; 95% confidence interval (CI) 0.71–0.77); but not in children (3.5% vs. 3.8%, respectively; OR = 0.91; 95%CI 0.76–1.10). Multivariate analysis showed in younger than 18 years that girls and immunosuppression were factors associated with a decrease in the odds to develop asthma. In adults, asthma was positively associated with females, obesity, smoking, immunosuppression, chronic obstructive pulmonary disease, arterial hypertension, and cardiovascular disease.

Conclusion:

The prevalence of asthma in child and adult were lower than those previously reported. Our study seems to support the hypothesis that asthma patients have a lower risk of SARS-CoV-2 infection. Further studies are required to demonstrate the consistency of our findings (AU)
Subject(s)


Full text: Available Collection: National databases / Spain Database: IBECS Main subject: Asthma / Coronavirus Infections / Pandemics Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Allergol. immunopatol Year: 2021 Document type: Article Institution/Affiliation country: Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”/México / Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca/México / Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”/México / Universidad Veracruzana/México

Full text: Available Collection: National databases / Spain Database: IBECS Main subject: Asthma / Coronavirus Infections / Pandemics Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Male Country/Region as subject: Mexico Language: English Journal: Allergol. immunopatol Year: 2021 Document type: Article Institution/Affiliation country: Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”/México / Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca/México / Nuevo Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”/México / Universidad Veracruzana/México
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