Immunogenic cell death (ICD)-inducers in non-small-cell lung carcinoma (NSCLC): current knowledge and future perspective
Clin. transl. oncol. (Print)
; 25(2): 316-322, feb. 2023.
Article
in English
| IBECS
| ID: ibc-215931
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
The prevalence of non-small-cell lung cancer (NSCLC) is rising every year all around the world. The interaction between cancer cells and the tumor microenvironment (TME) is a crucial factor in determining the development of human neoplasms. Organellar and cellular stress are induced during immunogenic cell death (ICD), a particularly functional response pattern. ICD is a separate but poorly characterized entity caused by various cancer treatments. The induction of ICD has the potential to change TME and the recruitment of tumor-infiltrating lymphocytes (TILs), and the coupling of ICD-inducers and other therapeutic approaches can have a synergistic role in boosting anticancer impacts. The purpose of this study is to review the studies in the field of NSCLC using ICD-inducers as a treatment strategy or as a combination therapy. This review provide for researches a better view of what has been done so far and the challenges they face in the future (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Cell Death
/
Carcinoma, Non-Small-Cell Lung
/
Antineoplastic Agents, Immunological
/
Lung Neoplasms
/
Antineoplastic Agents
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2023
Document type:
Article
Institution/Affiliation country:
Shahid Beheshti University of Medical Sciences/Iran
/
Tehran University of Medical Sciences/Iran