SARS-CoV-2 infection in patients with melanoma: results of the Spanish Melanoma Group registry
Clin. transl. oncol. (Print)
; 25(3): 768-775, mar. 2023.
Article
in English
| IBECS
| ID: ibc-216435
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background The Spanish Melanoma Group (GEM) developed a national registry of patients with melanoma infected by SARS-CoV-2 (GRAVID). Methods The main objective was to describe the COVID-19 fatality rate in patients with melanoma throughout the pandemic, as well as to explore the effect of melanoma treatment and tumor stage on the risk of COVID-19 complications. These are the final data of the register, including cases from February 2020 to September 2021. Results One hundred-fifty cases were registered. Median age was 68 years (range 695), 61 (40%) patients were females, and 63 (42%) patients had stage IV. Thirty-nine (26%) were on treatment with immunotherapy, and 17 (11%) with BRAF-MEK inhibitors. COVID-19 was resolved in 119 cases, including 85 (57%) patients cured, 15 (10%) that died due to melanoma, and 20 (13%) that died due to COVID-19. Only age over 60 years, cardiovascular disorders, and diabetes mellitus increased the risk of death due to COVID-19, but not advanced melanoma stage nor melanoma systemic therapies. Three waves have been covered by the register FebruaryMay 2020, AugustNovember 2020, and December 2020April 2021. The first wave had the highest number of registered cases and COVID-19 mortality. Conclusion Tumor stage or melanoma treatments are non-significant prognostic factors for COVID-19 mortality. During the pandemic in Spain there was a downward trend in the number of patients registered across the waves, as well as in the severity of the infection (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Skin Neoplasms
/
Coronavirus Infections
/
Pandemics
/
Melanoma
Limits:
Adolescent
/
Adult
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Aged
/
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Europa
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2023
Document type:
Article
Institution/Affiliation country:
Dexeus University Hospital/Spain
/
Hospital Clinico Universitario Virgen Arrixaca/Spain
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Hospital San Cecilio/Spain
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Hospital Universitario Central de Asturias/Spain
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Hospital Universitario Miguel Servet/Spain
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Hospital Universitario la Princesa/Spain
/
University of Barcelona/Spain
/
Xarxa Assistencial Universitària de Manresa/Spain