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Effect of strength training on people with HIV and immunometabolic disorders / Efecto del entrenamiento de fuerza en personas con VIH y trastornos inmunometabólicos
Santos, Wlaldemir R. dos; Santos, Walmir R. dos; Pinheiro Paes, Pedro; Tenório Ramos, Klaudia E; Dantas Botelho, Emerson H; Ferreira-Silva, Isac A; Queiroz Balbino, Valdir de; Morais Fernandes, Ana P.
Affiliation
  • Santos, Wlaldemir R. dos; University of São Paulo. School of Nursing of Ribeirão Preto. Ribeirão Preto. Brazil
  • Santos, Walmir R. dos; University of São Paulo. School of Physical Education and Sport of Ribeirão Preto. Ribeirão Preto. Brazil
  • Pinheiro Paes, Pedro; University Federal of Pernambuco. Physical Education Department. Recife. Brazil
  • Tenório Ramos, Klaudia E; University Federal of Pernambuco. Genetics Department. Recife. Brazil
  • Dantas Botelho, Emerson H; University Federal of Pernambuco. Physical Education Department. Recife. Brazil
  • Ferreira-Silva, Isac A; University of São Paulo. School of PhysicalEducation and Sport of Ribeirão Preto. Ribeirão Preto. Brazil
  • Queiroz Balbino, Valdir de; University Federal of Pernambuco. Biological Sciences Center. Recife. Brazil
  • Morais Fernandes, Ana P; University of São Paulo. School of Nursing of Ribeirão Preto. Ribeirão Preto. Brazil
Arch. med. deporte ; 38(203): 163-167, May. 2021. tab
Article in English | IBECS | ID: ibc-217897
Responsible library: ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
The introduction of highly active antiretroviral therapy (HAART) was able to help to control viral condition in patients livingwith HIV/AIDS, diminishing virus concentration and increasing T CD4 + cells. However, adverse effects follow the treatment,like lipodystrophy syndrome, characterized by morphological changes in body fat distribution and changes serum lipids andglycides levels, increasing the risk for chronical diseases with cardiovascular effects. Thus, complimentary non-drug practices,as strength training, are essential to treat these patients, helping to improve their immunometabolic condition, leading to abetter coping with the disease. The aim of this study was to investigate the influence of a 12-week strength training protocolon immunometabolic system of people living with HIV/AIDS. It is a quasi-experimental study, conducted on 20 patients (16men), all living with HIV/AIDS using HAART. T CD4 + cell numbers, serum triglycerides, cholesterol (total and fractions) andglycemia were measured before and after training. The data underwent to descriptive statistics using a paired T test, withthe significance level set at p <0.05.There was a significant increase of 15.4% (p=0.009) on T CD4 + cells and, although notstatistically significant, reduction on glycemia, total cholesterol and triglycerides and increase on HDL-cholesterol fraction.So, it is suggested that strength training may be effective on immunometabolic condition of people living with HIV / AIDS,increasing T CD4+ cells and controlling serum levels of lipids and glycides.(AU)
RESUMEN
La introducción de la terapia antirretroviral altamente activa (HAART) ayudó a controlar la condición viral de los pacientes con HIV/AIDS, reduciendo la concentración del virus y aumentando las células T CD4 +. Sin embargo, los efectos adversos acompañan el tratamiento, como el síndrome de lipodistrofia, caracterizada por cambios morfológicos en la distribución de la grasa corporal y de los niveles metabólicos en los lípidos y glicidos séricos, creciendo el riesgo de enfermedades crónicas con impacto cardiovascular. Así, los tratamientos complementarios no medicados, como el entrenamiento de fuerza, son esenciales en el tratamiento de estos pacientes, lo que contribuye en las mejoras inmunometabólicas en esta población, lo que contribuye a hacer frente a la enfermedad. El propósito de esta investigación fue verificar la influencia de un protocolode entrenamiento de fuerza con duración de 12 semanas en los sistemas inmunometabólicos de personas con HIV/SIDA.Este es un estudio cuasi-experimental, realizado con 20 pacientes (16 hombres), todos con HIV/SIDA usando la terapia HAART,sometidos a un protocolo de entrenamiento de fuerza de 12 semanas. Se tomaron medidas de las variables número de célulasT CD4 +, niveles séricos de triglicéridos, colesterol (total y fracciones) y glucosa en sangre, antes y después del entrenamiento.Los datos fueron analizados mediante estadística descriptiva, con prueba T pareada y nivel significativo establecido en p <0,05.El resultado mostró un aumento significativo en las células T CD4 + en un 15,4% (p=0,009), aunque no es estadísticamentesignificativo, tuve la glucosa en sangre reducida, así como el colesterol total y los triglicéridos, con respectivo aumento dela fracción de colesterol HDL. Por lo tanto, sugerimos que el entrenamiento de fuerza puede ser efectivo en las condicionesinmunológicas y metabólicas de las personas que viven con HIV/AIDS, aumentando las células T CD4 + y controlando los...(AU)
Subject(s)


Full text: Available Collection: National databases / Spain Database: IBECS Main subject: CD4-Positive T-Lymphocytes / Acquired Immunodeficiency Syndrome / HIV / Antiretroviral Therapy, Highly Active / Resistance Training / Lipodystrophy Limits: Adult / Female / Humans / Male Language: English Journal: Arch. med. deporte Year: 2021 Document type: Article Institution/Affiliation country: University Federal of Pernambuco/Brazil / University of São Paulo/Brazil

Full text: Available Collection: National databases / Spain Database: IBECS Main subject: CD4-Positive T-Lymphocytes / Acquired Immunodeficiency Syndrome / HIV / Antiretroviral Therapy, Highly Active / Resistance Training / Lipodystrophy Limits: Adult / Female / Humans / Male Language: English Journal: Arch. med. deporte Year: 2021 Document type: Article Institution/Affiliation country: University Federal of Pernambuco/Brazil / University of São Paulo/Brazil
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