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Seroprevalence of antibodies against SARS-CoV-2 in the Valencian Community (Spain) as of October 2022 / Seroprevalencia de anticuerpos frente al SARS-CoV-2 en la Comunidad Valenciana (España) en octubre de 2022
García-Sempere, Aníbal; Giménez, Estela; Limón, Ramón; Navarro, David; Vanaclocha, Hermelinda; Peiró, Salvador.
Affiliation
  • García-Sempere, Aníbal; , Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO). Health Services Research and Pharmacoepidemiology Unit. València. Spain
  • Giménez, Estela; Clinic University Hospital. Microbiology Service. INCLIVA Health Research Institute. València. Spain
  • Limón, Ramón; Valencian Government. General Directorate of Healthcare. Department of Health. València. Spain
  • Navarro, David; Clinic University Hospital. Microbiology Service. INCLIVA Health Research Institute. València. Spain
  • Vanaclocha, Hermelinda; Valencian Government. General Directorate of Public Health. Department of Health. València. Spain
  • Peiró, Salvador; Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO). Health Services Research and Pharmacoepidemiology Unit. València. Spain
Gac. sanit. (Barc., Ed. impr.) ; 37: 102312, 2023. tab
Article in En | IBECS | ID: ibc-222048
Responsible library: ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Objective: To estimate the seroprevalence of SARS-CoV-2 antibodies in the Valencian Community (Spain) in October 2022, when BA.5 was the predominant variant. Method: Cross-sectional, region-wide, population-based serosurvey study in 88 randomly selected primary care centers of the Valencian Community. Results: Seroprevalence of anti-nucleocapsid (indicative of past infection) and total receptor binding domain (indicative of past infection or vaccination) antibodies was 71.0% (confidence interval [CI]: 67.8-74.2) and 98.4% (CI: 97.5-99.3), respectively. 66.7% (CI: 63.4-70.0) of the population shows hybrid immunity, but only 43.2% in those 80 and over. Conclusions: The high proportion of hybrid immunity detected is relevant for public health strategies. A second vaccination booster was advisable in the elderly population.(AU)
RESUMEN
Objetivo: Estimar la seroprevalencia de anticuerpos frente al SARS-CoV-2 en la Comunidad Valenciana (España) en octubre de 2022, cuando BA.5 era la variante predominante. Método: Estudio transversal de base poblacional de ámbito autonómico en 88 centros de atención primaria de la Comunidad Valenciana seleccionados aleatoriamente. Resultados: La seroprevalencia de anticuerpos antinucleocápside (indicativos de infección previa) y frente al dominio de la unión al receptor (indicativos de infección o vacunación) fue del 71,0% (intervalo de confianza [IC]: 67,8-74,2) y del 98,4% (IC: 97,5-99,3), respectivamente. El 66,7% (IC: 63,4-70,0) de la población mostraba inmunidad híbrida, pero solo el 43,2% de los mayores de 80 años. Conclusiones: La alta proporción de inmunidad híbrida detectada era relevante para las estrategias de salud pública, pero era aconsejable un segundo refuerzo de vacunación en la población anciana.(AU)
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Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Seroepidemiologic Studies / Coronavirus Infections / Severe acute respiratory syndrome-related coronavirus / Pandemics / Antibodies Limits: Humans Country/Region as subject: Europa Language: En Journal: Gac. sanit. (Barc., Ed. impr.) Year: 2023 Document type: Article

Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Seroepidemiologic Studies / Coronavirus Infections / Severe acute respiratory syndrome-related coronavirus / Pandemics / Antibodies Limits: Humans Country/Region as subject: Europa Language: En Journal: Gac. sanit. (Barc., Ed. impr.) Year: 2023 Document type: Article