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Pharmaceutical interventions and factors associated with their acceptance in intensive care units in Brazil / Intervenciones farmacéuticas y factores asociados a su aceptación en unidades de cuidados intensivos en Brasil
Oliveira, Ana Vitória Martins de; Chaves, Elana Figueiredo; Conceição, Amanda Mota; Magalhães, Liana Moreira; Araújo, Breno Queiroz de; Andrade, Cinthya Cavalcante de; Alcântara Neto, José Martins de; Oliveira, Alene Barros de.
Affiliation
  • Oliveira, Ana Vitória Martins de; Federal University of Ceará. Walter Cantídio University Hospital. Multiprofessional Integrated Residency Program in Hospital Health Care. Fortaleza. Brazil
  • Chaves, Elana Figueiredo; Federal University of Ceará. Walter Cantídio University Hospital. Multiprofessional Integrated Residency Program in Hospital Health Care. Fortaleza. Brazil
  • Conceição, Amanda Mota; Federal University of Ceará. Walter Cantídio University Hospital. Multiprofessional Integrated Residency Program in Hospital Health Care. Fortaleza. Brazil
  • Magalhães, Liana Moreira; Federal University of Ceará. Walter Cantídio University Hospital. Multiprofessional Integrated Residency Program in Hospital Health Care. Fortaleza. Brazil
  • Araújo, Breno Queiroz de; Federal University of Ceará. Walter Cantídio University Hospital. Multiprofessional Integrated Residency Program in Hospital Health Care. Fortaleza. Brazil
  • Andrade, Cinthya Cavalcante de; Federal University of Ceará. Walter Cantídio University Hospital. hospital pharmacy service. Fortaleza. Brazil
  • Alcântara Neto, José Martins de; Federal University of Ceará. Walter Cantídio University Hospital. hospital pharmacy service. Fortaleza. Brazil
  • Oliveira, Alene Barros de; Federal University of Ceará. Walter Cantídio University Hospital. hospital pharmacy service. Fortaleza. Brazil
Ars pharm ; 64(3)jul.-sep. 2023. ilus, tab
Article in En | IBECS | ID: ibc-222345
Responsible library: ES1.1
Localization: ES15.1 - BNCS
RESUMEN
Objetivo: El propósito de este estudio es evaluar las intervenciones farmacéuticas (IF) realizadas sobre PRM y los factores asociados a su aceptación. Método: Se trata de un estudio descriptivo y transversal que analizó las IF realizadas a pacientes adultos de dos UCI de Fortaleza, Brasil, en 2019. Las IF se analizaron en las categorías cantidad de fármaco y estrategia farmacológica, utilizando la clasificación propuesta por Sabater et al. Los fármacos se clasificaron además por el Sistema de Clasificación Anatómica, Terapéutica, Química y por la clasificación de Fármacos de Alta Vigilancia (FAV). Resultados: Se incluyeron 305 pacientes, siendo la mayoría del sexo masculino (55,1 %), ancianos (52,8 %) y atendidos en la UCI quirúrgica (51,4 %). Se analizaron 1.317 IF y se aceptaron el 88,0 %, siendo la sustitución de uno o más fármacos (28,0 %) y la adición de uno o más fármacos (27,7 %) las más frecuentes. La clase terapéutica más prevalente fue antiinfeccioso de uso sistémico (24,1 %) y los FAV estuvieron implicados en el 21,7 % de las IF. Se observó asociación entre las IF aceptadas e ingreso en UCI clínica (p<0,0001), FAV (p=0,0013), sustitución de uno o más fármacos (p=0,0062) y la clase sustitutos sanguíneos y soluciones de perfusión (p= 0,0187). Conclusiones: Se realizaron y aceptaron un elevado número de IF, lo que refuerza la importancia del farmacéutico en la revisión de las prescripciones médicas en UCI. (AU)
ABSTRACT
Objective: The purpose of this study is to evaluate the pharmaceutical interventions (PI) performed in PRM and the factors associated with their acceptance.Method: This is a descriptive and cross-sectional study that analyzed PIs performed on adult patients from two ICUs in Fortaleza, Brazil, in 2019. PIs were analyzed in the categories quantity of drug and pharmacological strategy, using the classification proposed by Sabater et al. The drugs were also classified by the Anatomical, Therapeutic, and Chemical Classification System and by the High Surveillance Drugs (FAV) classification.Results: 305 patients were included, most of them male (55.1 %), elderly (52.8 %) and treated in the surgical ICU (51.4 %). 1,317 PIs were analyzed and 88.0 % were accepted, being to replace one or more drugs (28.0 %), to add one or more drugs (27.7 %) and to change the dose (24.8 %) the most frequent types. The most prevalent therapeutic class was anti-infectives for systemic use (24.1 %) and AVFs were involved in 21.7 % of the PIs. An association was observed between PIs accepted and admission to the clinical ICU (p<0.0001), AVF (p=0.0013), substitution of one or more drugs (p=0.0062) and the class of blood substitutes and perfusion solutions. (p= 0.0187).Conclusions: A high number of PIs were performed and accepted, which reinforces the importance of the pharma-cist in the review of medical prescriptions in the ICU. (AU)
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Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Pharmaceutical Services / Drug Therapy Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Ars pharm Year: 2023 Document type: Article

Full text: 1 Collection: 06-national / ES Database: IBECS Main subject: Pharmaceutical Services / Drug Therapy Limits: Adult / Aged / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Ars pharm Year: 2023 Document type: Article