Sex differences in the diagnosis, treatment and prognosis of cancer: the rationale for an individualised approach
Clin. transl. oncol. (Print)
; 25(7): 2069-2076, jul. 2023. tab, graf
Article
in English
| IBECS
| ID: ibc-222378
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background Precision medicine in oncology aims to identify the most beneficial interventions based on a patients individual features and disease. However, disparities exist when providing cancer care to patients based on an individuals sex. Objective To discuss how sex differences impact the epidemiology, pathophysiology, clinical manifestations, disease progression, and response to treatment, with a focus on data from Spain. Results Genetic and environmental factors (social or economic inequalities, power imbalances, and discrimination) that contribute to these differences adversely affect cancer patient health outcomes. Increased health professional awareness of sex differences is essential to the success of translational research and clinical oncological care. Conclusions The Sociedad Española de Oncología Médica created a Task Force group to raise oncologists awareness and to implement measures to address sex differences in cancer patient management in Spain. This is a necessary and fundamental step towards optimizing precision medicine that will benefit all individuals equally and equitably (AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Sex Characteristics
/
Precision Medicine
/
Neoplasms
Limits:
Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Clin. transl. oncol. (Print)
Year:
2023
Document type:
Article
Institution/Affiliation country:
CIBERONC/Spain
/
Navarras Health Research Institute/Spain
/
University General Hospital Morales Meseguer/Spain
/
University Hospital La Fe/Spain
/
University Hospital Puerta de Hierro/Spain