Pattern of drug therapy related problems encountered by clinical pharmacists in a critical care setting in Nepal
Pharm. pract. (Granada, Internet)
; 21(2): 1-11, abr.-jun. 2023. tab, graf
Article
in English
| IBECS
| ID: ibc-222795
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background:
Most hospitalized patients experience Drug Therapy-Related Problems (DTRPs) resulting in morbidity, mortality, and an increase in the cost of treatment. DTRPs are an important issue and a serious yet preventable problem.Objective:
To identify DTRPs in the department of critical care medicine of a tertiary care center in Nepal.Methods:
This was a cross-sectional study carried out at the department of critical care medicine in a tertiary care hospital in Kathmandu, Nepal from August to November 2021. All the patients admitted to ICU/ high care unit (HCU) for more than 48 hours during the study period were recruited in this study. Two clinical pharmacists visited the ICU/ HCU daily to identify any drug therapy-related problems. The Pharmaceutical Care Network Europe (PCNE) Classification system version 9.1 was referred for the classification of identified DTRPs. Descriptive statistics were applied for demographic variables. The Chi-square test was used for categorical variables. Pearson correlation was used to study the relationship between patient variables and the number and types of DTRPs.Results:
DTRPs were identified in 74.2% (n=89) of patients. More than one DTRP was identified in 38.5% of patients. The identified DTRPs were primarily classified into two sections Problems and Causes. A total of 106 problems were identified among which unnecessary drug treatment (40.5%, n=43) was the most common problem. For the causes total of 137 were identified, out of which the drug and dose selection accounted for 44.5 and 16.8%, respectively. The average DTRP per patient was 1.5± 0.7. Antibiotics 30 (22%) and multivitamins, 10 (7%) were the maximal involved in DTRPs. More DTRPs were observed in male patients (n=60, 80%). The association between dose selection and gender was significant. Drug selection issues were observed more in patients prescribed multiple drugs and with a shorter hospital stay. (AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Pharmacists
/
Drug Therapy
/
Intensive Care Units
Limits:
Adolescent
/
Adult
/
Aged
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Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Pharm. pract. (Granada, Internet)
Year:
2023
Document type:
Article
Institution/Affiliation country:
Ajman University/United Arab Emirates
/
Grande International Hospital/Nepal
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International Medical University/Nepal
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KIST Medical College and Teaching Hospital/Nepal