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Pattern of drug therapy related problems encountered by clinical pharmacists in a critical care setting in Nepal
Acharya, Upasana; Shankar, P Ravi; Palaian, Subish; Dangol, Resha; Jha, Nisha; Thakur, Anand.
Affiliation
  • Acharya, Upasana; Grande International Hospital. Dhapasi. Nepal
  • Shankar, P Ravi; International Medical University. IMU Centre for Education. FAcadMed. Kuala Lumpur. Nepal
  • Palaian, Subish; Ajman University. College of Pharmacy and Health Sciences. Ajman. United Arab Emirates
  • Dangol, Resha; Grande International Hospital. Dhapasi. Nepal
  • Jha, Nisha; KIST Medical College and Teaching Hospital. Imadol. Nepal
  • Thakur, Anand; Grande International Hospital. Consultant Intensivist. Dhapasi. Nepal
Pharm. pract. (Granada, Internet) ; 21(2): 1-11, abr.-jun. 2023. tab, graf
Article in English | IBECS | ID: ibc-222795
Responsible library: ES1.1
Localization: ES15.1 - BNCS
ABSTRACT

Background:

Most hospitalized patients experience Drug Therapy-Related Problems (DTRPs) resulting in morbidity, mortality, and an increase in the cost of treatment. DTRPs are an important issue and a serious yet preventable problem.

Objective:

To identify DTRPs in the department of critical care medicine of a tertiary care center in Nepal.

Methods:

This was a cross-sectional study carried out at the department of critical care medicine in a tertiary care hospital in Kathmandu, Nepal from August to November 2021. All the patients admitted to ICU/ high care unit (HCU) for more than 48 hours during the study period were recruited in this study. Two clinical pharmacists visited the ICU/ HCU daily to identify any drug therapy-related problems. The Pharmaceutical Care Network Europe (PCNE) Classification system version 9.1 was referred for the classification of identified DTRPs. Descriptive statistics were applied for demographic variables. The Chi-square test was used for categorical variables. Pearson correlation was used to study the relationship between patient variables and the number and types of DTRPs.

Results:

DTRPs were identified in 74.2% (n=89) of patients. More than one DTRP was identified in 38.5% of patients. The identified DTRPs were primarily classified into two sections Problems and Causes. A total of 106 problems were identified among which unnecessary drug treatment (40.5%, n=43) was the most common problem. For the causes total of 137 were identified, out of which the drug and dose selection accounted for 44.5 and 16.8%, respectively. The average DTRP per patient was 1.5± 0.7. Antibiotics 30 (22%) and multivitamins, 10 (7%) were the maximal involved in DTRPs. More DTRPs were observed in male patients (n=60, 80%). The association between dose selection and gender was significant. Drug selection issues were observed more in patients prescribed multiple drugs and with a shorter hospital stay. (AU)
Subject(s)


Full text: Available Collection: National databases / Spain Database: IBECS Main subject: Pharmacists / Drug Therapy / Intensive Care Units Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Pharm. pract. (Granada, Internet) Year: 2023 Document type: Article Institution/Affiliation country: Ajman University/United Arab Emirates / Grande International Hospital/Nepal / International Medical University/Nepal / KIST Medical College and Teaching Hospital/Nepal

Full text: Available Collection: National databases / Spain Database: IBECS Main subject: Pharmacists / Drug Therapy / Intensive Care Units Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: Asia Language: English Journal: Pharm. pract. (Granada, Internet) Year: 2023 Document type: Article Institution/Affiliation country: Ajman University/United Arab Emirates / Grande International Hospital/Nepal / International Medical University/Nepal / KIST Medical College and Teaching Hospital/Nepal
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