High performance of the automated ADVIA Centaur Systems SARS-CoV-2 Antigen Assay in nasopharyngeal samples with high viral load / Alto rendimiento del ensayo de antígeno ADVIA Centaur Systems SARS-CoV-2 automatizado en muestras nasofaríngeas con alta carga viral
Int. microbiol
; 26(3): 471-474, Ene-Agos, 2023. ilus, graf
Article
in English
| IBECS
| ID: ibc-223974
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
ADVIA Centaur SARS-CoV-2 Antigen (COV2Ag) Assay (Siemens Healthineers) was evaluated for SARS-CoV-2 detection. A total of 141 nasopharyngeal samples were analyzed by this technique and results were compared with those obtained by quantitative reverse-transcription polymerase chain reaction (RT-PCR). The overall sensitivity and specificity of the test were 68.70% and 70%, respectively. Regarding cycle threshold (Ct) values, the COV2Ag test showed a sensitivity of 93.75% and 100% for nasopharyngeal samples with Ct < 25 and < 20, respectively. ADVIA Centaur COV2Ag Assay is a useful, automated, and rapid technique for early SARS-CoV-2 diagnosis and isolation of the infected individuals, avoiding its transmission.(AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Polymerase Chain Reaction
/
Sensitivity and Specificity
/
Viral Load
/
Severe acute respiratory syndrome-related coronavirus
Limits:
Humans
Language:
English
Journal:
Int. microbiol
Year:
2023
Document type:
Article
Institution/Affiliation country:
Hospital Clínico San Carlos/Spain
/
Universidad Complutense Madrid/Spain
/
Universidad Complutense de Madrid/Spain