Clinical Practice Guideline of Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on Pharmacological Treatment of Tobacco Dependence 2023
Arch. bronconeumol. (Ed. impr.)
; 59(10): 651-661, oct. 2023. ilus, tab
Article
in English
| IBECS
| ID: ibc-226193
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Introduction:
There are multiple systematic reviews and meta-analyses on the efficacy and safety of pharmacological treatments against nicotine dependence. However, there are few guidelines to answer frequent questions asked by a clinician treating a smoker. Therefore, the aim of this paper is to facilitate the treatment of tobacco addiction. Material andmethods:
12 PICO questions are formulated from a GLOBAL PICO question Efficacy and safety of pharmacological treatment of tobacco dependence. A systematic review was carried out to answer each of the questions and recommendations were made. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation) system was used to grade the certainty of the estimated effects and the strength of the recommendations.Results:
Varenicline, nicotine replacement therapy (NRT), bupropion and cytisine are more effective than placebo. Varenicline and combined nicotine therapy are superior to the other therapies. In smokers with high dependence, a combination of drugs is recommended, being more effective those associations containing varenicline. Other optimization strategies with lower efficacy consist of increasing the doses, the duration, or retreat with varenicline. In specific populations varenicline or NRT is recommended. In hospitalized, the treatment of choice is NRT. In pregnancy it is indicated to prioritize behavioral treatment. The financing of smoking cessation treatments increases the number of smokers who quit smoking. There is no scientific evidence of the efficacy of pharmacological treatment of smoking cessation in adolescents.Conclusions:
The answers to the 12 questions allow us to extract recommendations and algorithms for the pharmacological treatment of tobacco dependence. (AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Thoracic Surgery
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Tobacco Use Disorder
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Pulmonary Medicine
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Smoking Cessation
Limits:
Adolescent
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Female
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Humans
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Pregnancy
Language:
English
Journal:
Arch. bronconeumol. (Ed. impr.)
Year:
2023
Document type:
Article
Institution/Affiliation country:
Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela/Spain
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Hospital Carlos Haya de Málaga/Spain
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Hospital Clínico San Carlos/Spain
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Hospital Clínico Universitario de Valencia/Spain
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Hospital Universitario 12 de octubre Madrid/Spain
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Hospital Universitario Fundación Alcorcón/Spain
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Hospital Universitario San Juan de Alicante/Spain
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Hospital Universitario Virgen de la Victoria/Spain
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Hospital Universitario de Cáceres/Spain