Maximal Respiratory Pressure Reference Equations in Healthy Adults and Cut-off Points for Defining Respiratory Muscle Weakness
Arch. bronconeumol. (Ed. impr.)
; 59(12): 813-820, dic. 2023. tab, graf, mapas
Article
in English
| IBECS
| ID: ibc-228401
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Introduction:
Maximal inspiratory and expiratory pressures (PImax/PEmax) reference equations obtained in healthy people are needed to correctly interpret respiratory muscle strength. Currently, no clear cut-off points defining respiratory muscle weakness are available. We aimed to establish sex-specific reference equations for PImax/PEmax in a large sample of healthy adults and to objectively determine cut-off points for respiratory muscle weakness.Methods:
A multicentre cross-sectional study was conducted across 14 Spanish centres. Healthy non-smoking volunteers aged 1880 years stratified by sex and age were recruited. PImax/PEmax were assessed using uniform methodology according to international standards. Multiple linear regressions were used to obtain reference equations. Cut-off points for respiratory muscle weakness were established by using T-scores.Results:
The final sample consisted of 610 subjects (314 females; 48 [standard deviation, SD 17] years). Reference equations for PImax/PEmax included body mass index and a squared term of the age as independent variables for both sexes (p<0.01). Cut-off points for respiratory muscle weakness based on T-scores ≥2.5 SD below the peak mean value achieved at a young age were 62 and 83cmH2O for PImax and 81 and 109cmH2O for PEmax in females and males, respectively.Conclusion:
These reference values, based on the largest dataset collected in a European population to date using uniform methodology, help identify cut-off points for respiratory muscle weakness in females and males. These data will help to better identify the presence of respiratory muscle weakness and to determine indications for interventions to improve respiratory muscle function. (AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Respiratory Insufficiency
/
Maximal Respiratory Pressures
Limits:
Adult
/
Aged
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Female
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Humans
/
Male
Country/Region as subject:
Europa
Language:
English
Journal:
Arch. bronconeumol. (Ed. impr.)
Year:
2023
Document type:
Article
Institution/Affiliation country:
Hospital Clínic of Barcelona/Spain
/
Ramon Llull University/Spain
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Research Group or Rehabilitation in Internal Disorders/Belgium
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University Autónoma of Madrid/Spain
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University of A Coruña/Spain
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University of Chile/Chile
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University of Deusto/Spain