The role of gastrointestinal endoscopy in Kaposi sarcoma / El papel de la endoscopia gastrointestinal en el sarcoma de Kaposi
Rev. esp. enferm. dig
; 115(12): 724-725, Dic. 2023. ilus
Article
in English
| IBECS
| ID: ibc-228715
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
We are writing to make endoscopists aware of the paramount of a prompt diagnosis of gastrointestinal Kaposi sarcoma (GI-KS). Patients with GI involvement have a two to five times higher risk of death and will benefit from chemotherapy to improve their survival. However, current evidence found that one out of three patients might have a false negative result even with HHV-8 since other entities such as gastrointestinal stromal tumors, angiosarcoma, and lymphoma shared macroscopic and histopathological characteristics. These cause a delay in treatment and significantly worsen the prognosis. We observed a trend for a positive diagnosis from ulcers and nodules. To our knowledge, this is the largest cohort of patients with GI-KS in the world. Our study suggests that in cases where a complete immunochemistry panel for KS is not available, HHV-8 remains as a bare minimum. However, other gastrointestinal lesions shared histopathological characteristics. Therefore, we suggest taking biopsies from nodular and ulcer-type lesions to increase the probability to establish a histopathological diagnosis.(AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Sarcoma, Kaposi
/
Endoscopy, Gastrointestinal
/
Eosine Yellowish-(YS)
/
Herpesvirus 8, Human
/
Gastrointestinal Stromal Tumors
/
Hematoxylin
Limits:
Humans
Language:
English
Journal:
Rev. esp. enferm. dig
Year:
2023
Document type:
Article
Institution/Affiliation country:
Instituto Nacional de Cancerología/Mexico