Application of Real-Time Ultrasound ElastographyCombined with Prostate Calcification in Differential Diagnosis of Prostate Cancer

ABSTRACT

Objective: This study aimed to explore the clinical and differential diagnostic value of real-time ultrasound elastography combinedwith transabdominal prostate calcification in prostate cancer (PCa).Methods: This study retrospectively analysed the clinical pathological data of 97 patients with PCa and 105 patients with benignprostatic hyperplasia (BPH) diagnosed by postoperative pathology in our hospital from May 2020 to May 2021; Comparativelyanalysed the clinical data of the two groups, including the elastic strain ratio, elastic image compression index, types of prostatecalcification and calcification diameter; And used logistic regression analysis to screen out the independent risk factors for identifyingPCa and BPH.Results: No significant difference in age, body weight, body mass index, location of calcification and calcification diameter wasobserved between the two groups (p > 0.05), and overt differences in elastic strain ratio, elastic image compression index, typesof calcification, and testosterone were found between the PCa group and BPH group (p < 0.05). Logistic regression analysisshowed that the elastic strain ratio, elastic image compression index and types of calcification were independent risk factors foridentifying PCa (p < 0.05). The area under curve value of combined diagnosis under receiver operating characteristic curve wasas high as 0.756 (95% CI 0.691–0.813), with a sensitivity of 67.60% and a specificity of 76.30%.Conclusions: A certain correlation is observed amongst elastic strain ratio, elastic image compression index, types of prostatecalcification and the occurrence and development of PCa. The application of real-time ultrasound elastography combined withthe detection of transabdominal prostate calcification in clinical diagnosis can improve the detection rate of PCa, which has animportant clinical application value. (AU)