Effect of caloric restriction and low fructose consumption on oxidative damage in adults with obesity / Efecto de la restricción calórica y el bajo consumo de fructosa sobre el daño oxidativo en adultos con obesidad
Nutr. clín. diet. hosp
; 44(1): 290-294, Feb. 2024. tab
Article
in English
| IBECS
| ID: ibc-231325
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Background:
The consumption of macronutrients rich insugars, mainly fructose, promote metabolic changes and in-duce insulin resistance, hepatic and extrahepatic fatty aciddeposits, as well as an increase in the generation of free rad-icals and oxidative stress.Methods:
Randomized clinical study, 74 subjects partici-pated, divided into 2 group a calorie-restricted diet (n=37)and a low-fructose diet (n=37). They were evaluated at thebeginning and 6 weeks after the implementation of the diet,using anthropometric and biochemical parameters. Descriptivestatistics were used to analyze the data, Students t test fortwo independent samples considering unequal variances andfor means of two paired samples. Level p<0.05 was consid-ered in each analysis test.Results:
The body mass index (BMI) shows statisticallysignificant differences p< 0.05 in the group with calorie re-striction after applying the diet. The waist and hip circumfer-ence were modified by the implementation of the diet in eachindependent group (p<0.001 for each statistical difference,respectively), only the waist-hip index (WHR) was modifiedwhen the results were compared between both groups,p<0.05. In the biochemical parameters after the implementa-tion of the diets, in the low-fructose diet group an increase inblood glucose was observed from 175.97 to 187.40 mg/dl,cholesterol from 34.05 to 36.89 mg/dl and HDL from 104.77to 115.47 mg/dl. However, no statistically significant differ-ences were found when comparing both groups. No statisti-cally significant differences were observed in lipid peroxida-tion parameters or oxidized carbonyls.Conclusion:
The modifications in hepatic metabolismcould be related to the energy quantity and the source ofmacronutrients.(AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Insulin Resistance
/
Caloric Restriction
/
Eating
/
Feeding Behavior
/
Fructose
/
Obesity
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Nutr. clín. diet. hosp
Year:
2024
Document type:
Article
Institution/Affiliation country:
Campus Celaya-Salvatierra/México
/
Campus León/México