Epithelial and stromal thickness profile and lens decentration in myopic orthokeratology / Perfil de espesor epitelial y estromal y descentrado del cristalino en ortoqueratología miope
J. optom. (Internet)
; 17(2): [100485], Abr-Jun, 2024. tab, ilus
Article
in English
| IBECS
| ID: ibc-231620
Responsible library:
ES1.1
Localization: ES15.1 - BNCS
ABSTRACT
Purpose:
To study topographic epithelial and total corneal thickness changes in myopic subjects undergoing successful orthokeratology treatment in connection with the objective assessment of contact lens decentration.Methods:
A prospective-observational and non-randomized study in 32 Caucasian myopic eyes undergoing Ortho-k for 3 months. Total, epithelial, and stromal thicknesses were studied before and after Ortho-k treatment, using optical coherence tomography with anterior segment application software. Central, paracentral, and mid-peripheral values are taken along 8 semi-meridians.Results:
The central average total corneal thickness was 4.72 ± 1.04 μm thinner after Ortho-K. The paracentral corneal thickness showed no significant changes (p = 0.137), while the mid-peripheral corneal thickness was increased by 3.25 ± 1.6 μm associating this increase exclusively to the epithelial plot (p<0.001). When lens centration was assessed, a lens fitting decentration less than 1.0 mm was found for the whole sample, predominantly horizontal-temporal (87.5%) and vertical-inferior (50%) decentring. Corneal topographical analysis revealed a horizontal and vertical epithelial thickness asymmetric change profile with paracentral temporal thinnest values, and mid-peripheral nasal thickest values.Conclusions:
The present study found a central corneal thinning induced by Ortho-k lenses in subjects with moderate myopia, only associated with a change in epithelial thickness, as well as mid-peripheral thickening, that seems to be mainly epithelial in origin. The authors also found a tendency of contact lens decentration toward temporal and inferior areas conditioning an asymmetric epithelial redistribution pattern.(AU)
Full text:
Available
Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Vision, Ocular
/
Corneal Stroma
/
Tomography, Optical Coherence
/
Orthokeratologic Procedures
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Lens, Crystalline
/
Myopia
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
J. optom. (Internet)
Year:
2024
Document type:
Article
Institution/Affiliation country:
Universidade de Santiago de Compostela/Spain