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ABC transporters in the protozoan parasite Leishmania
Pérez-Victoria, José; Parodi-Talice, Adriana; Torres, Cristina; Gamarro, Francisco; Castanys, Santiago.
Affiliation
  • Pérez-Victoria, José; Instituto de Parasitología y Biomedicina López-Neira. Granada. España
  • Parodi-Talice, Adriana; Instituto de Parasitología y Biomedicina López-Neira. Granada. España
  • Torres, Cristina; Instituto de Parasitología y Biomedicina López-Neira. Granada. España
  • Gamarro, Francisco; Instituto de Parasitología y Biomedicina López-Neira. Granada. España
  • Castanys, Santiago; Instituto de Parasitología y Biomedicina López-Neira. Granada. España
Int. microbiol ; 4(3): 159-166, sept. 2001. ilus
Article in En | IBECS | ID: ibc-23248
Responsible library: ES1.1
Localization: ES1.1 - BNCS
ABSTRACT
ATP-binding cassette (ABC) transporters constitute one of the biggest and most conserved protein families in the evolutionary scale. Many of them are of enormous clinical relevance, due to their relationship with genetic diseases and drug resistance during the treatment of cancer and infectious diseases. Leishmaniasis is a major and globally widespread group of parasitic diseases, whose treatment has been complicated by the expansion of resistance to conventional drugs. Here, we review the current knowledge about ABC transporters in Leishmania spp, with special attention to their relationship with the drug-resistance phenotype (AU)
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Collection: 06-national / ES Database: IBECS Main subject: Leishmaniasis / ATP-Binding Cassette Transporters / Leishmania Limits: Animals Language: En Journal: Int. microbiol Year: 2001 Document type: Article
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Collection: 06-national / ES Database: IBECS Main subject: Leishmaniasis / ATP-Binding Cassette Transporters / Leishmania Limits: Animals Language: En Journal: Int. microbiol Year: 2001 Document type: Article