Revisión sistemática y metaanálisis de la eficacia diagnóstica de la PET 18F-FDG en recurrencia tumoral de cánceres de cabeza y cuello / Systematic review and meta-analysis of diagnostic accuracy of 18F-FDG PET in suspected recurrent head and neck cancer
Acta otorrinolaringol. esp
; Acta otorrinolaringol. esp;59(4): 190-197, abr. 2008. ilus, tab
Article
in Es
| IBECS
| ID: ibc-64040
Responsible library:
ES15.1
Localization: ES15.1 - BNCS
Objetivos: En este trabajo se realizó un metaanálisis de la literatura para evaluar la exactitud diagnóstica de la PET 18F-FDG en la sospecha de recurrencia de cánceres de cabeza y cuello. Material y métodos: Inicialmente se realizó una búsqueda sistemática de la literatura en las fuentes MEDLINE y CANCERLITE hasta mayo de 2007, aplicando unos criterios de cribado a los estudios hallados. Se calcularon los valores de sensibilidad, especificidad, cocientes de probabilidad positivo y negativo y la odds ratio diagnóstica. El rendimiento diagnóstico se valoró mediante curvas ROC (receive-operating-characteristic). Resultados: Fueron incluidos 19 artículos en el metaanálisis. La sensibilidad de la PET 18F-FDG fue del 94 %, la especificidad del 80 % y la curva ROC mostró una buena relación entre sensibilidad y especificidad. Conclusiones: La PET 18F-FDG fue útil en pacientes con sospecha de recurrencia tumoral por cáncer de cabeza y cuello; mostró una sensibilidad alta y una especificidad intermedia-alta
Objectives: A meta-analysis of the literature was performed in this article in order to evaluate the diagnostic accuracy of 18F-FDG PET in suspected recurrent head and neck cancer. Material and methods: A systematic review of the literature was performed using 1987 to 2007 MEDLINE and CANCERLIT databases, applying selection criteria to the studies found. Sensitivity, specificity, positive and negative likelihood ratios, and odds ratio were calculated. The diagnostic accuracy was evaluated with ROC (receive-operating-characteristics) curves. Results: Nineteen articles were included in the meta-analysis. Sensitivity of 18F-FDG PET was 94 %, specificity 80 %, and the summary ROC curve showed a good trade-off between sensitivity and specificity. Conclusions: 18F-FDG PET was useful in patients with suspected recurrence of head and neck cancer, showing a high sensitivity and intermediate-high specificity
Objectives: A meta-analysis of the literature was performed in this article in order to evaluate the diagnostic accuracy of 18F-FDG PET in suspected recurrent head and neck cancer. Material and methods: A systematic review of the literature was performed using 1987 to 2007 MEDLINE and CANCERLIT databases, applying selection criteria to the studies found. Sensitivity, specificity, positive and negative likelihood ratios, and odds ratio were calculated. The diagnostic accuracy was evaluated with ROC (receive-operating-characteristics) curves. Results: Nineteen articles were included in the meta-analysis. Sensitivity of 18F-FDG PET was 94 %, specificity 80 %, and the summary ROC curve showed a good trade-off between sensitivity and specificity. Conclusions: 18F-FDG PET was useful in patients with suspected recurrence of head and neck cancer, showing a high sensitivity and intermediate-high specificity
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Collection:
06-national
/
ES
Database:
IBECS
Main subject:
Tomography, Emission-Computed
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Head and Neck Neoplasms
/
Neoplasm Recurrence, Local
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Systematic_reviews
Limits:
Female
/
Humans
/
Male
Language:
Es
Journal:
Acta otorrinolaringol. esp
Year:
2008
Document type:
Article