Altas tasas de incidencia de enfermedad inflamatoria intestinal en Navarra. Resultados de un estudio prospectivo y poblacional / High incidence rates of inflammatory bowel disese in Navarra (Spain). Results of a prospective, population-based study

ABSTRACT

INTRODUCTION: As reflected in the European Collaborative Study on Inflammatory Bowel Disease (1991-1993), differencesbetween northern and southern European countries in theincidence of ulcerative colitis (UC) and Crohn’s disease (CD)show a tendency to decrease. No data are available on the currentincidence of these diseases in Navarre (northern Spain).AIM: To determine the present incidence of inflammatorybowel disease (IBD) in Navarra.PATIENTS AND METHODS: A prospective, population-basedstudy was performed to determine the incidence of IBD inNavarra between 2001 and 2003. Total population: 569,628inhabitants (284,620 males). All cases of IBD diagnosed inany public or private hospital in Navarre were included inthe study. Crude rates and age- and sex-specific rates adjustedto the European standard population were calculated.RESULTS: A total of 288 cases were diagnosed (UC 176, CD102, indeterminate colitis 10). Crude rates of UC, CD andindeterminate colitis were 10.29, 5.96 and 0.58 cases/100,000inhabitants/year respectively (the population aged 0-14 yearsof age was included). Specific rates were 9.57 (95% CI,7.27-12.57) and 5.85 (95% CI, 3.99-8.14) cases/100,000 inhabitants/year for UC and CD, respectively.CONCLUSIONS: The incidence of UC and CD in Navarra hasincreased in the last decade, with rates close to those of northernEuropean countries and higher than those recently published in Spanish prospective studies (AU)