Sarcoma sinovial: hallazgos morfológicos en un caso estudiado por punción aspiración con aguja fina / Synovial sarcoma: morphological findings in a case studied with fine needle aspiration

ABSTRACT

Introduction: The frequent use of fine needle aspiration (FNA) as a diagnostic technique, applicable to the study of tumours accessible both radiologically and by simple palpation requires that pathologists must have an increasingly profound knowledge of the cytological aspects of the lesions, both of the most frequent and elementary types and those that are only observed rarely in daily clinical practice. Case report: Male, aged 42, with a 3.5 cm mass, during the last 10 months, palpable, and located in submaxillar area. FNA showed abundant cellular material, mainly composed of fusiform elements, with high nuclear-cytoplasmic ration. Cellular block sections confirmed fusocelular elements that were positive for vimentin and focally positive for cytokeratin (CK) AE1/AE3, and CK7 and 19. They were negative for actin, desmin, HMB-45, calretinin, S-100, and CD31. A diagnosis of suggestive of sarcoma was made. Surgical excision of the tumour allowed a histopathological diagnosis of biphasic synovial sarcoma, which was confirmed by cytogenetic studies. Conclusion: The traditional advantages of FNA (speed, harmlessness, low cost) may sometimes be accompanied by the possibility of extending the cytological study to the fields of histology and immunocytochemistry through the handling of cell blocks (AU)