Mucormicosis rinoorbitocerebral, un estudio retrospectivo de 7 casos / Rhino-orbito-cerebral mucormycosis, a retrospective study of 7 cases
Acta otorrinolaringol. esp
; 61(1): 48-53, ene.-feb. 2010. tab, ilus
Article
in Spanish
| IBECS
| ID: ibc-76422
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
La mucormicosis es una infección oportunista, producida por los hongos del orden mucorales. Tiene una baja incidencia. Es potencialmente letal y afecta a pacientes inmunocomprometidos. Presentamos 7 casos de mucormicosis rinocerebral en un estudio retrospectivo de 8 años (20002008) en pacientes hematológicos. Es preciso realizar un diagnóstico precoz, para lo cual se ha de mantener un alto índice de sospecha clínica en pacientes con factores predisponentes. El diagnóstico de certeza requiere la realización de cultivos o biopsias de las zonas afectadas que demuestren la invasión de los tejidos por las hifas características. La clave del tratamiento es el desbridamiento quirúrgico precoz y agresivo, junto con altas dosis de amfotericina B intravenosa. A pesar de este tratamiento, el pronóstico es desfavorable y la mortalidad es de un 7080% (AU)
ABSTRACT
Mucormycosis is an opportunistic fungal infection caused by fungi of the Mucorales order. It has a low incidence and is a potentially lethal infection which generally affects patients who are immunocompromised due to systemic disease. We report 7 cases of rhinocerebral mucormycosis in a retrospective study of 8 years (20002008) in hematologyc patients. An early diagnosis is essential, and therefore there must be a high level of clinical suspicion in patients with predisposing factors. Certainty diagnosis requires fungal cultures or biopsies of the affected areas which prove an invasion of the tissues by the characteristic hyphae. The key to treatment is early and aggressive surgical treatment, together with high intravenous doses of B amphotericyn. Despite this, prognosis is poor and mortality is about 7080% (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Opportunistic Infections
/
Amphotericin B
/
Endoscopy
/
Mucormycosis
Type of study:
Observational study
/
Prognostic study
/
Risk factors
/
Screening study
Limits:
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Acta otorrinolaringol. esp
Year:
2010
Document type:
Article
Institution/Affiliation country:
Hospital Universitario de Salamanca/España