Relationship between oral Kaposi ’s sarcoma and HAART: Contribution of two case reports

ABSTRACT

Two HIV infected patients not receiving Highly Active Antiretroviral Treatment (HAART) presented with epidemicKaposi’s sarcoma of the oral cavity. One patient initially refused HAART, but when the lesion became large enoughto be noticeable he agreed to HAART associated with excision of the intraoral lesion by CO2 laser. The other patientdeveloped KS and progressed to AIDS at two years after ceasing HAART due to adverse effects; he was referred tohospital for renewed administration of HAART. In both cases, the lesions observed in the oral cavity were the firstclinical manifestation of AIDS. These reports underline the close relationship between the use of HAART and thecontrol of KS lesions, highlighting the important role of the dentist in the identification and early diagnosis of these oral lesions (AU)