Hybrid salivary gland tumor of the upper lip or just anadenoid cystic carcinoma? Case report

ABSTRACT

A 65 year-old male patient with a one year-duration tumoral growth located in the upper lip was diagnosed onincisional biopsy as epithelial-myoepithelial carcinoma. After wide surgical excision the histopathological analysisrevealed the lesion was composed predominantly (>90%) of adenoid cystic carcinoma. In new sections it wasfound a very small and isolated area of adenoid cystic carcinoma at the bottom of the incisional biopsy. As surgicalmargins were free of lesion, no adjuvant treatment was given. The occurrence of a transitory ischaemic attackat 36 months of follow-up led to a neurological and MRI evaluation, which disclosed a well-defined 3.5x3 cmlesion suggestive of metastasis, located on the right temporal area. The lesion was surgically removed and a histopathologicaldiagnosis of neurocysticercosis was rendered. After 40 months of follow-up there is no evidence ofrecurrence. Conclusion: True hybrid tumors of salivary glands are rare and treatment in each case should be doneaccording to the component with the higher aggressiveness. However, the occurrence of epithelial-myoepithelialcarcinoma areas within an adenoid cystic carcinoma seems to be a frequent finding, and because both lesions sharea common origin, some authors consider that this may not be a true hybrid neoplasm but a variant of the latter (AU)

RESUMEN

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