Pustulosis exantemática aguda generalizada inducida por omeprazol / Acute generalized exanthematous pustulosis induced by omeprazole
Gastroenterol. hepatol. (Ed. impr.)
; 31(5): 295-298, mayo 2008. tab, ilus
Article
in Spanish
| IBECS
| ID: ibc-84647
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
La pustulosis exantemática aguda generalizada (PEAG) englobaun subgrupo de erupciones, caracterizadas por la apariciónde numerosas pústulas estériles sobre un fondo eritematosoedematoso.Generalmente, son inducidas por fármacos y suscaracterísticas indican un trasfondo inmunológico. El tratamientoconsiste en la supresión del fármaco responsable. Engeneral, el pronóstico es bueno, y la lesión cutánea se resuelveen unos pocos días, con su peculiar descamación.Presentamos 3 casos de PEAG inducidos por omeprazol, unfármaco con un excelente perfil de seguridad, entre cuyosefectos secundarios se han descrito varios tipos de lesionescutáneas, sin que hayamos encontrado en la revisión bibliográficaninguna referencia a casos de PEAG por este fármaco.La PEAG relacionada con otros inhibidores de la bombade protones es excepcional (AU)
ABSTRACT
generalized exanthematous pustulosis (AGEP) comprisesa group of eruptions characterized by several smallsterile pustules over an erythematous-edematous skin. Theseeruptions are usually drug induced and show some characteristicsthat suggest an immunologic background. Treatmentis based on withdrawal of the drug causing the eruption.Prognosis is generally good and the skin lesions usuallyresolve in a few days with characteristic postpustular pinpointdesquamation.We report three cases of AGEP induced by omeprazole, adrug with a good safety profile. Some adverse cutaneous reactionshave been described as secondary effects. However,to our knowledge, no cases of omeprazole-induced AGEPhave previously been reported. AGEP related to other protonpump inhibitors is exceptional (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Omeprazole
/
Exanthema
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Gastroenterol. hepatol. (Ed. impr.)
Year:
2008
Document type:
Article
Institution/Affiliation country:
Hospital de Navarra/España