Factores de riesgo ambientales no dietéticos en el cáncer de próstata / Constitutional Risk Factors In Prostate Cancer
Actas urol. esp
; 35(5): 289-295, mayo 2011.
Article
in Spanish
| IBECS
| ID: ibc-88836
Responsible library:
ES1.1
Localization: BNCS
RESUMEN
Introducción:
Se pretende actualizar y divulgar los principales factores de riesgo ambientales, excluyendo los dietéticos, implicados en la etiopatogenia del cáncer de próstata. Material ymétodo:
Revisión bibliográfica de los últimos 25 años de los factores de riesgo ambientales no dietéticos asociados a cáncer de próstata entre 1985 y 2010, obtenida del Med-Line, CancerLit, Science Citation Index y Embase. Los perfiles de búsqueda han sido Environmental Risk Factors/Tobacco/Infectious-Inlammation Factors/Pesticides/Vasectomy/OccupationalExposures/Chemoprevention Agents/Radiation y «Cáncer de Próstata».Resultados:
Mientras que algunos factores de riesgo ambientales no dietéticos incrementan el riesgo de padecer la enfermedad, otros lo disminuyen. Entre los primeros destacan la exposición al humo del tabaco; los procesos prostáticos infecto-inflamatorios crónicos y la exposición profesional al cadmio, herbicidas y pesticidas. Los principales factores que reducen el riesgo es elempleo de fármacos quimiopreventivos (finasterida, dutasterida) y la exposición a la radiación ultravioleta solar. La vasectomía, con los datos actuales, no influye en el riesgo de desarrollarla enfermedad.Conclusiones:
El lento proceso de carcinogénesis prostática es el resultado final de la interacción de factores de riesgo constitucionales y ambientales. Los factores ambientales no dietéticos desempeñan un papel importante en la etiopatogenia de esta enfermedad. Para valorar apropiadamente los factores de riesgo deben analizarse grandes casuísticas que incluyan todas las variables posibles (AU)ABSTRACT
Introduction:
The aim is to update and disclose the main environmental risk factors, excluding dietary factors, involved in the etiopathology of prostate cancer. Materials andmethod:
Bibliographic review of the last 25 years of non-dietary environmental risk factors associated with prostate cancer between 1985 and 2010, obtained from MedLine, CancerLit, Science Citation Index and Embase. The search profiles were Environmental RiskFactors/Tobacco/Infectious-Inflammatory Factors/Pesticides/Vasectomy/Occupational Exposures/Chemoprevention Agents/Radiation and Prostate Cancer.Results:
While some non-dietary environmental risk factors increase the risk of acquiring the disease, others decrease it. Of the former, it is worth mentioning exposal to tobacco smoke, chronic infectious-inflammatory prostatic processes and occupational exposure to cadmium, herbicides and pesticides. The first factors that reduce the risk are the use of chemopreventive drugs (Finasterida, Dutasteride) and exposure to ultraviolet solar radiation. With the current data, a vasectomy does not influence the risk of developing the disease.Conclusions:
The slow process of prostate carcinogenesis is the final result of the interaction of constitutional risk and environmental factors. Non-dietary environmental factors play an important role in the etiopathology of this disease. To appropriately assess the risk factors, extensive case studies that include all the possible variables must be analysed (AU)
Full text:
Available
Collection:
National databases
/
Spain
Health context:
SDG3 - Target 3.9 Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil
/
Sustainable Health Agenda for the Americas
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SDG3 - Health and Well-Being
Health problem:
Occupational Exposures
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Goal 9: Noncommunicable diseases and mental health
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Target 3.4: Reduce premature mortality due to noncommunicable diseases
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Target 3.9: Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil
Database:
IBECS
Main subject:
Tobacco Smoke Pollution
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Epidemiology
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Risk Factors
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Environmental Exposure
Type of study:
Etiology study
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Risk factors
Limits:
Adult
/
Aged
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Humans
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Male
Language:
Spanish
Journal:
Actas urol. esp
Year:
2011
Document type:
Article
Institution/Affiliation country:
Centro de Salud de Chella/España
/
Hospital Infantil Universitario La Fe/España
/
Hospital Materno-Infantil Universitario Virgen de la Arrixaca/España
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Hospital de Sagunt/España
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Mount Sinai International Exchange Program/EE. UU