Oxidative stress status in patients with chronic idiopathic urticaria
Allergol. immunopatol
; 39(3): 150-153, mayo-jun. 2011. tab
Article
in English
| IBECS
| ID: ibc-90103
Responsible library:
ES1.1
Localization: BNCS
ABSTRACT
Aim:
The controversial data related to oxidative stress status in patients with chronic idiopathic urticaria (CIU) have been reported. Therefore, the present study was aimed to contribute to this debate by determining oxidative stress markers along with some trace element levels inpatients with CIU.Methods:
Twenty-five patients with CIU (10 males, 15 females) and 36 healthy controls were enrolled into the study. Erythrocyte lipid peroxidation status, scavenger enzyme activities and trace element levels were determined.Results:
While erythrocyte MDA levels, erythrocyte GSH- Px activities and erythrocyte Zn levels showed no differences between the patient and control groups, a statistically significant decrease and increase were observed in erythrocyte CuZn-SOD activities and Cu levels, respectively, in the CIU patients when compared to those of the controls (p < 0.001 for both of them).Conclusion:
In conclusion, an oxidative burden which can be relieved by some preserved antioxidant mechanisms seems to be present in patients with CIU even if they are clinically stable and it may probably have a role in the pathogenesis (AU)
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Collection:
National databases
/
Spain
Database:
IBECS
Main subject:
Urticaria
/
Free Radical Scavengers
/
Oxidative Stress
/
Lipid Peroxides
/
Malondialdehyde
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Allergol. immunopatol
Year:
2011
Document type:
Article
Institution/Affiliation country:
Gulhane Military Medical Academy Etlik/Turkey