Fluoride concentration and pH of pediatric medicines regularyand long-term used by children

ABSTRACT

Objectives: Our aim in this study was to determine the fluoride concentration and pH of 71 pediatric medicinesregularly and long-term used by children.Study Design: The fluoride concentration was evaluated by selective electrode of fluoride (Orion). The pH wasconfronted using specific electrode (Orion) coupled to a potentiometer (Orion). The analyses were accomplishedin duplicate. Pearson´s correlation and Kruskal-Wallis test were used. P-values below 5% were considered statisticallysignificant.Results: Medicine pH averages ± SD varied from 2.3 ±0.01 to up 10.6 ±0.02. Values below critical pH were observedin 42.25% (n=30) of presentations, with 25.35% (n=18) below 4.5 pH. Most medicines (84.5%) presentedfluoride concentration below 0.05 mg/L.Conclusions: Among the pediatric medicines evaluated, this study has showed that 2-4 times-a-day posology andsyrup formulations presented lowest pH and fluoride concentration, resulting in factors that predict highest cariogenicand erosive potential (AU)

RESUMEN

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