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Sensibilidad antimicrobiana de cepas hipurato-negativas de Campylobacter spp. y de Helicobacter pullorum aisladas de enfermos con diarrea / Antimicrobial sensitivity of hippurate-negative Campylobacter and Helicobacter pullorum strains isolated from patients with diarrhea
Bascuñana, Patricia; Pena, Irene; Picazo, Juan J; Velasco, Aurelio C.
Affiliation
  • Bascuñana, Patricia; Hospital Clínico San Carlos. Madrid. España
  • Pena, Irene; Hospital Clínico San Carlos. Madrid. España
  • Picazo, Juan J; Hospital Clínico San Carlos. Madrid. España
  • Velasco, Aurelio C; Hospital Clínico San Carlos. Madrid. España
Rev. esp. quimioter ; 24(4): 213-216, dic. 2011. tab
Article in Spanish | IBECS | ID: ibc-93788
Responsible library: ES1.1
Localization: BNCS
RESUMEN
El género Campylobacter, tanto C. jejuni como algunas especies hipurato-negativas y géneros relacionados, son la principal causa de gastroenteritis en nuestro entorno a lo largo de todo el año. El objetivo del presente estudio es determinar la sensibilidad de cepas hipurato negativas de Campylobacter spp. y de Helicobacter pullorum aislados de heces diarreicas humanas. Se estudiaron 39 cepas de Campylobacter coli, dos de C. lari y cinco de Helicobacter pullorum identificadas por espectrometría de masas MALDI-TOF. La sensibilidad a amoxicilina- clavulánico, eritromicina, azitromicina, gentamicina, ciprofloxacino, levofloxacino, tetraciclina, tigeciclina y cloranfenicol se determinó por E-test. La mayoría de las cepas de Campylobacter hipurato-negativos y H. pullorum estudiadas presentaron una elevada resistencia a las dos fluoroquinolonas probadas y a la tetraciclina. Por otro lado, todas las cepas fueron sensibles a amoxicilina-clavulánico, a tigeciclina y a cloranfenicol, mientras que la mayoría lo fueron a los macrólidos y a la gentamicina(AU)
ABSTRACT
C. jejuni as well as some hippurate-negative Campylobacter species and related diarrheagenic organisms, are the leading cause of gastroenteritis in our environment all throughout the year. The aim of the present study was to determine the sensitivity of hippurate-negative Campylobacter and Helicobacter pullorum strains isolated from the stools of patients with diarrhea. We tested 39 Campylobacter coli, two C. lari and five Helicobacter pullorum strains identified by mass spectrometry analysis. The sensitivity to amoxicillin-clavulanic acid, erytrhomycin, azithromycin, gentamicin, ciprofloxacin, levofloxacin, tetracycline, tigecycline and chloramphenicol was tested by E-test. Most hippurate-negative Campylobacter and H. pullorum isolates studied showed high resistance to tetracycline and to the two fluorquinolones tested. On the other side, all strains were sensitive to amoxicillin-clavulanic acid, tigecycline and chloramphenicol, while most of them were sensitive to both macrolides tested and to gentamicin(AU)
Subject(s)
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Collection: National databases / Spain Health context: Neglected Diseases Health problem: Diarrhea / Neglected Diseases Database: IBECS Main subject: Campylobacter / Campylobacter Infections / Hippurates / Anti-Infective Agents Type of study: Diagnostic study Language: Spanish Journal: Rev. esp. quimioter Year: 2011 Document type: Article Institution/Affiliation country: Hospital Clínico San Carlos/España
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Collection: National databases / Spain Health context: Neglected Diseases Health problem: Diarrhea / Neglected Diseases Database: IBECS Main subject: Campylobacter / Campylobacter Infections / Hippurates / Anti-Infective Agents Type of study: Diagnostic study Language: Spanish Journal: Rev. esp. quimioter Year: 2011 Document type: Article Institution/Affiliation country: Hospital Clínico San Carlos/España
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