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Possível envolvimento dopaminérgico na resposta febril induzida pelo lipopolissacarídeo de E. coli, no coelho / Dopaminergic involvement in the fever response induced in rabbits by lipopolysaccharide from E. coli
Camargo Neves, Maria do Carmo Longo; Pelá, Irene Rosemir.
Rev. ciênc. farm ; 12: 31-8, 1990. ilus
Article in Portuguese | LILACS | ID: lil-167852
Responsible library: BR33.1
RESUMO
Drogas neurolépticas como a clorpromazina (CLOR), flufenazina (Flu), haloperidol (HAL) e pinozide (Pim), conhecidas por atuarem como antipsicóticas e bloqueadoras de receptores dopaminérgicos centrais, inibiram parcialmente a resposta febril induzida pelo lipopolissacarídeo de E. coli (LPS), um pirogênio bacteriano, em coelhos. Os presentes resultados sugerem que os receptores dopaminérgicos centrais podem estar envolvidos nessa resposta febril, muito embora essa mobilizaçäo näo represente o principal mecanismo
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Collection: International databases Health context: Neglected Diseases Health problem: Neglected Diseases / Zoonoses Database: LILACS Main subject: Pimozide / Dopamine Agents / Chlorpromazine / Lipopolysaccharides / Escherichia coli Infections / Fever / Fluphenazine / Haloperidol Limits: Animals Language: Portuguese Journal: Rev. ciênc. farm Journal subject: Pharmacology Year: 1990 Document type: Article
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Collection: International databases Health context: Neglected Diseases Health problem: Neglected Diseases / Zoonoses Database: LILACS Main subject: Pimozide / Dopamine Agents / Chlorpromazine / Lipopolysaccharides / Escherichia coli Infections / Fever / Fluphenazine / Haloperidol Limits: Animals Language: Portuguese Journal: Rev. ciênc. farm Journal subject: Pharmacology Year: 1990 Document type: Article