The incidence of lethal graft-versus-host disease in rat limb allotransplantations
Rev. Hosp. Säo Paulo Esc. Paul. Med
; 6(1/2): 7-10, Jan.-Jun. 1995. ilus
Article
in English
| LILACS
| ID: lil-179684
Responsible library:
BR1.1
ABSTRACT
To study graft-versus-host disease (GVHD) in rat hindlimb allotransplantation, a model similar to intestinal transplantation was used. ACI and Lewis rats were crossed to produce F(1) generation rats (ACI-Lewis). These underwent limb transplantation receiving a donor limb from a Lewis rat. The animals were examined daily and skin biopsies were performed. Results showed that all limbs were viable at 34 weeks and no rats demonstrated any clinical evidence of GVHD and biopsies were grade 0.
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Collection:
International databases
Database:
LILACS
Main subject:
Extremities
/
Graft vs Host Disease
Type of study:
Incidence study
/
Prognostic study
/
Risk factors
Limits:
Animals
Language:
English
Journal:
Rev. Hosp. Säo Paulo Esc. Paul. Med
Journal subject:
Medicine
Year:
1995
Document type:
Article