Cytomegalovirus infection in children: frequency, anatomopathologic characteristics and underlying risk factors in 1618 autopsies
Arch. med. res
; 27(1): 25-30, 1996. tab, ilus
Article
in English
| LILACS
| ID: lil-200286
Responsible library:
MX1.1
RESUMO
The aim of this study was to determine the frequency of cytomegalovirus (CMV) infection in children with postmortem study. The records of 1618 autopsies performed during 1980 - 1989 at the Hospital Infantil de Mexico Federico Gomez were reviewed. Characteristic cytomegalovirus inclusion bodies were identified, in one or several organs, in 47 cases (2.9 per cent of the autopsies). None of these cases was cultured for viruses prior to ar at the time of autopsy. Of the 47 cases, 24 (51 per cent) with CMV were younger than 3 months of age. In eight cases, the infection was juged as generalized and considered the cause of death. Two of these patients were premature and the infection was most probably intrauterine. The risk factor most frequently identified was secondary immunosuppression. The lung was the most common affected organ, followed by kidney, adrenals, pancreas, liver, brain and salivary glands. In seven cases the inclusion bodies were seen in the brain and in three others periventricular calcifications without inclusion bodies were observed. Although not a rarity in Mexico, CMV infection is not often suspected. Additional studies are needed in order to determine the prevalence of CMV infection in Mexico
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Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
LILACS
Main subject:
Uterine Diseases
/
Health Surveys
/
Immunocompromised Host
/
Lung Diseases, Interstitial
/
Cytomegalovirus Infections
/
Infectious Mononucleosis
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Language:
English
Journal:
Arch. med. res
Journal subject:
Medicine
Year:
1996
Document type:
Article