Spinal cord compression in beta-thalassemia: follow-up after radiotherapy
São Paulo med. j
; 116(6): 1879-81, nov.-dez. 1998. ilus
Article
in English
| LILACS
| ID: lil-229429
Responsible library:
BR1.1
ABSTRACT
Context Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including beta-thalassemia. Case Report We report the case of a patient with intermediate beta-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. Discussion:
Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Spinal Cord Compression
/
Hematopoiesis, Extramedullary
/
Beta-Thalassemia
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
São Paulo med. j
Journal subject:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicine
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Year:
1998
Document type:
Article
Affiliation country:
Brazil