Cell envelope components of Yersinia pestis grown in intraperitoneal diffusion chambers
Rev. microbiol
; 29(3): 174-8, jul.-set. 1998. ilus, graf
Article
in English
| LILACS
| ID: lil-236203
Responsible library:
BR32.1
ABSTRACT
The electrophoretic profiles binding of penicillin binding proteins (PBPs) and outer membrane proteins (OMPs) of Yersinia pestis EV 76 were determined following in vivo growth in diffusion chambers implanted in the peritoneal cavity of mice. In contrast to Y. pestis grown under in vitro conditions which activate the low calcium response (LCR) regulon there was no significant qualitative or quantitative change of the PBP profile of Y. pestis cells during growth in diffusion chambers for up to 72 h following implatation in mice. Three OMPs, with molecular weight of 100, 60 and 58 kDa, were expressed in Y. pestis cells grown for 24 h, but not at 48 h or at 72 h, in diffusion chambers. These results indicate that growth of Y. pestis in intraperitoneal diffusion chambers activates genes which might be relevant to the growth in the mammal host.
Full text:
Available
Collection:
International databases
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
LILACS
Main subject:
Penicillins
/
Yersinia pestis
/
Carrier Proteins
/
Membrane Proteins
Type of study:
Qualitative research
Limits:
Animals
Language:
English
Journal:
Rev. microbiol
Journal subject:
Microbiology
Year:
1998
Document type:
Article
Affiliation country:
Brazil