Pouchitis: extracolonic manifestation of ulcerative colitis?
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
; 54(5): 155-8, Sept.-Oct. 1999. tab
Article
in English
| LILACS
| ID: lil-255571
Responsible library:
BR1.1
RESUMO
Pouchitis is the most frequent complication of ileal pouch-anal anastomosis for treatment of ulcerative colitis. There are several possible explanations. Among them, we focus on the one that considers pouchitis as an extracolonic manifestation of ulcerative colitis. The aim of this study was to investigate the association between pouchitis and extra-intestinal manifestations (EIM), which are frequent in these patients. Sixty patients underwent restorative proctocolectomy with an ileal J pouch (IPAA) from September 1984 to December 1998. Pouchitis was defined by clinical, endoscopic, and histologic criteria. The following extra-intestinal manifestations were studied articular, cutaneous, hepatobiliary, ocular, genitourinary, and growth failure. Thirteen patients, of which 10 were female (76.9 percent), developed one or more episodes of pouchitis. Twelve patients of this group (92.3 percent) presented some kind of extra-intestinal manifestation, 4 pre-operatively (exclusively), 2 post-operatively (exclusively), and 6 both pre- and post-operatively (1.7 per patient). Twenty patients (42.7 percent) of the 47 without pouchitis did not present extra-intestinal manifestations; 10/35 (28.5 percent) of females had pouchitis, compared to 3/35 (12.0 percent) of men. Pouchitis was more frequent among females, though not statistically significant. EIM increases the risk of pouchitis. Pouchitis is related to EIM in 92.3 percent of cases, corroborating the hypothesis that it could be an extracolonic manifestation of ulcerative colitis
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Colitis, Ulcerative
/
Pouchitis
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. Hosp. Clin. Fac. Med. Univ. Säo Paulo
Journal subject:
Medicine
Year:
1999
Document type:
Article