Aspects of gastrointestina; immunology and nutrition in human immunodeficiency virus-1 infection in Brazil
Mem. Inst. Oswaldo Cruz
; 95(supl.1): 171-3, 2000.
Article
in English
| LILACS
| ID: lil-274877
Responsible library:
BR1.1
ABSTRACT
Mucosal surfaces have a fundamental participation in many aspects of the human immunodeficiency virus (HIV) infection pathogenesis. In Brazilian HIV-1 infected subjects, loss of weight and appetite are among the most debilitating symptoms. In this review we describe a defined mucosal immunogen that has profound but transient effects on HIV viral load, and we suggest that gut associated lymphoid tissue under constant immunostimulation is likely to provide a major contribution to the total levels of HIV. We also show that hypermetabolism appears to play a role in the wasting process in Brazilian patients coinfected with HIV and tuberculosis
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Tuberculosis
Database:
LILACS
Main subject:
HIV Infections
/
HIV-1
/
Immunity, Mucosal
/
Nutrition Disorders
Type of study:
Etiology study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2000
Document type:
Article
/
Congress and conference
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Oswaldo Cruz. Departamento de Imunologia/BR